Medication-Assisted Treatment (MAT) Centers
Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.
Found 300 treatment centers offering medication-assisted treatment (mat) across the United States.
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AdCare Hospital, located in Warwick, Rhode Island, specializes in outpatient treatment for substance abuse and provides targeted assistance for adults dealing with both substance use disorders and significant mental health issues, as well as emotional disturbances in minors. The center employs a variety of techniques, including 12-step support, anger management strategies, and brief intervention methods. They offer personalized programs designed for adult men, adult women, and clients facing co-occurring disorders, ensuring that each individual receives the care they need. This facility caters to both adult and young adult clients, focusing on delivering high-quality care and extensive support for individuals on their journey to recover from addiction and mental health difficulties.

Nestled in Worcester, MA, AdCare Hospital delivers a full spectrum of addiction recovery programs for adults and adolescents. They excel in medical detox, comprehensive substance abuse treatment, and care for dual diagnoses. This inpatient facility emphasizes 12-step integration, anger management techniques, and short-term intervention strategies. AdCare Hospital features distinct tracks for adult males, adult females, and those experiencing co-occurring conditions, addressing a variety of individual requirements. Their commitment to high-standard care and personalized recovery pathways positions them as a premier destination for those pursuing successful rehabilitation within a nurturing setting.

Located in Warwick, RI, AdCare Outpatient delivers an array of effective treatment options for individuals dealing with substance use issues and concurrent mental health conditions. The center features dedicated tracks for both adults and young adults, offering various levels of care including intensive outpatient, outpatient, and standard outpatient services. Employing strategies such as 12-step programs, anger management techniques, and brief interventions, AdCare Outpatient serves a diverse clientele, accommodating both men and women, including adult females. The center’s emphasis on addressing co-occurring disorders distinguishes its approach, ensuring thorough care for patients experiencing multifaceted challenges. AdCare Outpatient is committed to providing high-quality, personalized treatment aimed at fostering enduring recovery.

AdCare Outpatient in Worcester, MA, provides robust outpatient treatment for individuals grappling with substance use and concurrent mental health conditions. They serve adults and young adults with distinct programs for men, women, and those experiencing dual diagnoses. Employing methodologies such as 12-step support, emotional regulation techniques, and short-term counseling, the center delivers thorough and customized care. They offer various levels of care, including outpatient, day programs, and partial hospitalization, all delivered with a commitment to gender-specific services. AdCare Outpatient is dedicated to using proven therapeutic strategies and developing individualized recovery plans, promoting successful rehabilitation for those facing addiction and mental wellness issues.

AdCare Rhode Island Inc, located in Wakefield, RI, specializes in treating individuals with substance use issues and co-occurring mental health disorders for both adults and children. The center features a range of programs including intensive outpatient, outpatient, and partial hospitalization, employing evidence-based methods such as 12-step facilitation and anger management techniques. AdCare caters to the specific needs of various groups, including active duty military personnel, adult men and women. This facility focuses on providing high-quality, personalized care to ensure successful recovery for individuals of all genders. Whether individuals require substance use treatment or combined mental health services, AdCare Rhode Island Inc delivers thorough support in a nurturing setting.

AdCare Rhode Island Inc, located in Greenville, RI, focuses on providing targeted treatment for substance use and co-occurring mental health disorders in both adults and children facing emotional challenges. The center offers a variety of programs, including intensive outpatient, outpatient, and standard outpatient options, employing established techniques such as cognitive behavioral therapy, brief interventions, and anger management. With specific programs designed to meet the needs of adult men, women, and individuals with dual diagnoses, this center serves a diverse population of adults and seniors. AdCare Rhode Island Inc is distinguished by its thorough care, personalized treatment strategies, and dedication to high-quality service, positioning it as a leading option for individuals in need of effective rehabilitation support.

AdCare Rhode Island Inc., located in North Kingstown, RI, is dedicated to providing thorough addiction recovery solutions for adults and young adults. This facility offers extended stay residential care, inpatient detox, and round-the-clock residential treatment. Their programs are designed to address detoxification, the complexities of substance use, and the challenges of co-occurring mental health conditions. AdCare Rhode Island Inc. has tailored offerings for active military personnel, adult men, and adult women, demonstrating a commitment to personalized support. Employing strategies such as 12-step integration, emotional regulation techniques, and brief intervention methods, the center prioritizes customized care plans. Serving all genders, AdCare Rhode Island Inc. delivers effective, research-supported treatment for individuals striving to overcome addiction and concurrent mental health issues.

AdCare Rhode Island Inc. in North Kingstown provides outpatient programs for adults struggling with substance use, including individuals who also experience significant mental health concerns. The center offers tailored services for adult women and those with co-occurring mental health and substance use issues. Their approach incorporates 12-step facilitation, anger management techniques, and brief intervention strategies, serving adult men and women, as well as young adults. AdCare Rhode Island Inc. is dedicated to delivering personalized treatment and employing scientifically proven methods to support recovery from addiction and mental health difficulties.

Located in Decatur, IN, Adams Behavioral Health provides outpatient services aimed at treating substance abuse and concurrent mental health issues in both adults and children. The center employs techniques like cognitive behavioral therapy, motivational interviewing, and anger management to deliver personalized treatment that meets diverse needs. It also features specialized programs designed for clients involved with the criminal justice system. Catering to adults and senior individuals regardless of gender, the facility emphasizes high-quality care grounded in evidence-based methods. Committed to a holistic approach to healing and recovery, Adams Behavioral Health stands as a reliable option for those in need of thorough and individualized rehabilitation assistance.

Adams Cnty Integrated Healthcare Servs, located in Othello, WA, specializes in extensive substance abuse recovery programs. This facility offers a variety of treatment options, including intensive outpatient and standard outpatient services. Emphasizing techniques such as 12-step programs, brief interventions, and cognitive behavioral therapy, the center provides personalized care tailored to the specific needs of each client. It also features dedicated programs for adolescents as well as adult men and women, accommodating a wide array of individuals. Catering to adults and seniors of every gender, the center fosters a nurturing atmosphere for healing. Adams Cnty Integrated Healthcare Servs is dedicated to providing exceptional support to help individuals attain long-term recovery.

Adams Recovery Center, located in Loveland, OH, features a wide array of evidence-based services for addiction treatment. This facility focuses on detoxification and support for substance use disorders, offering a variety of programs including intensive outpatient care, long-term residential stays, and outpatient options for adults and young adults. With an emphasis on cognitive behavioral therapy, relapse prevention strategies, and counseling for substance use disorders, the center effectively serves both men and women. The personalized programs designed for different client demographics ensure that each individual receives dedicated care and assistance. Adams Recovery Center is recognized for its dedication to providing high-quality care and a holistic approach to recovery.

Adams Recovery Center, situated in New Richmond, OH, delivers comprehensive, science-backed therapies for those battling addiction. Their services include medical detox, structured outpatient care, extended stay residential treatment, and flexible outpatient options. Employing proven methods like cognitive behavioral therapy, relapse management, and addiction counseling, the center serves adult men, adult women, and young adults. By offering distinct programs for various demographics, Adams Recovery Center prioritizes personalized healing for enduring sobriety. Clients can anticipate thorough assistance and expert care from dedicated specialists at this respected recovery facility.

Adanta Group, located in Greensburg, KY, provides extensive outpatient services for both adults and children facing substance use issues, especially those with concurrent severe mental health challenges or emotional struggles. This center focuses on specific therapies, including anger management, cognitive behavioral therapy, and the Matrix Model, offering routine outpatient services alongside methadone/buprenorphine or naltrexone treatments. The programs are designed to support pregnant or postpartum women, as well as adults and seniors of all backgrounds. Emphasizing personalized treatment and proven methods, the center is dedicated to delivering top-notch care for individuals aiming to overcome addiction and mental health difficulties.

The Adanta Group, situated in Liberty, KY, provides extensive outpatient services for individuals of all ages struggling with substance use disorders, including those with co-occurring mental health challenges. Employing proven therapeutic methods like cognitive behavioral therapy, anger management, and the Matrix Model, the center delivers individualized treatment plans. They uniquely support pregnant and postpartum women, demonstrating a dedication to diverse needs. Serving adult and senior men and women, the Adanta Group fosters a welcoming atmosphere. Clients can anticipate excellent care and customized support, whether they require standard outpatient services or specialized methadone/buprenorphine treatment.

Adanta Group, located in Campbellsville, KY, specializes in outpatient treatment for adults dealing with substance use issues, particularly those with concurrent severe mental health conditions. They also extend their services to children experiencing significant emotional challenges. The center offers various treatment modalities, including outpatient programs involving methadone, buprenorphine, or naltrexone, alongside standard outpatient services to meet diverse patient requirements. By applying evidence-based methods such as cognitive behavioral therapy, anger management, and the Matrix Model, Adanta Group ensures an all-encompassing approach to treatment. Additionally, it features specialized programs for pregnant and postpartum women, distinguishing it from other facilities. The center serves adults and seniors of all gender identities, emphasizing personalized and high-quality rehabilitation care.

Adanta Group located in Glasgow, KY, specializes in outpatient care for adults and children facing substance abuse and concurrent mental health issues. The center employs various methodologies such as anger management, cognitive behavioral therapy, and the Matrix Model to customize treatment plans according to individual requirements. It also provides dedicated programs for pregnant or postpartum women, ensuring a wide range of support for different groups. Adanta Group serves adults and seniors of all genders and is committed to delivering high-quality, evidence-informed care to assist in the recovery process. Individuals in need of outpatient methadone or buprenorphine therapy, along with standard outpatient services, can receive tailored assistance at this center.

Situated in Whitley City, KY, the Adanta Group delivers targeted treatment for substance use issues alongside co-existing mental health challenges. This center provides outpatient care options, including treatments with methadone, buprenorphine, or naltrexone, customized for both adults and children. Utilizing evidence-based methodologies such as cognitive behavioral therapy, anger management, and the Matrix Model, the facility ensures thorough support. Importantly, the Adanta Group offers specific programs for women who are pregnant or in the postpartum phase and serves both male and female clients of all ages. Committed to high-quality and personalized treatment, this center stands as a vital resource for individuals on their recovery journey.

Situated in Somerset, KY, the Adanta Group delivers targeted outpatient services for individuals battling substance abuse and concurrent severe mental health issues in adults, as well as significant emotional challenges in children. This center offers a range of treatment modalities, including outpatient methadone, buprenorphine, or naltrexone therapies, along with standard outpatient support. Emphasizing techniques such as anger management, cognitive behavioral therapy, and the Matrix Model, the facility customizes its services to meet each client's specific needs. Specialized programs for pregnant and postpartum women, together with resources available for adults and seniors across all genders, facilitate thorough and inclusive care. The Adanta Group is recognized for its exceptional treatment quality and varied therapeutic strategies.

Situated in Monticello, KY, the Adanta Group delivers extensive outpatient services for adults dealing with substance use disorders alongside significant mental health challenges, as well as for children facing serious emotional difficulties. With expertise in areas such as anger management, cognitive behavioral therapy, and the Matrix Model, this center offers consistent outpatient treatment and medications like methadone, buprenorphine, or naltrexone. Tailored programs are available for pregnant and postpartum women, and the facility caters to adults and seniors across all genders. The Adanta Group is dedicated to providing high-quality care grounded in evidence-based practices to support individuals on their recovery journey.

The Adanta Group in Jamestown, KY, provides expert outpatient care for individuals of all ages struggling with substance use and related mental health conditions. This center prioritizes personalized treatment, offering options such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside routine outpatient counseling and dedicated support for pregnant and postpartum women. Employing proven therapeutic methods including anger management, cognitive behavioral therapy, and the Matrix Model, the Adanta Group serves a diverse clientele, from adults to seniors, across all genders. Its dedication to gender-sensitive services and customized recovery strategies makes it a leading destination for effective rehabilitation.

Adanta Group in Albany, KY, provides outpatient addiction services for adults and youth facing concurrent severe mental health conditions. Their specialized care includes programs for expectant and new mothers, incorporating techniques like anger management, cognitive behavioral therapy, and the Matrix Model. Patients can receive personalized outpatient care with methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Adanta Group, catering to individuals of all ages and genders, emphasizes personalized approaches and proven therapeutic strategies to deliver complete assistance for recovery.
Frequently Asked Questions
What is Medication-Assisted Treatment (MAT)?
What medications are used in MAT?
Is MAT just replacing one addiction with another?
How long does MAT last?
Does insurance cover MAT?
About Medication-Assisted Treatment (MAT)
Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.
MAT Medications for Opioid Use Disorder
Three FDA-approved medications treat opioid addiction:
- Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
- Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
- Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.
MAT for Alcohol Use Disorder
FDA-approved medications for alcohol addiction:
- Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
- Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
- Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking
Comprehensive Treatment Approach
MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.
Addressing Stigma and Misconceptions
MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.
Finding MAT Treatment
Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.
Harm Reduction and Medication-Assisted Treatment
Harm reduction is a public health philosophy that meets people where they are in their relationship with substance use. Rather than demanding abstinence as a precondition for support, harm reduction focuses on reducing the negative health, social, and economic consequences of drug use while keeping individuals alive, safe, and connected to care. This pragmatic approach recognizes that not everyone is ready or able to stop using substances immediately, and that incremental steps toward health are meaningful and worth supporting.
Harm reduction programs take many forms in communities across the country. Needle exchange and syringe service programs reduce the spread of HIV and hepatitis C among people who inject drugs. Naloxone (Narcan) distribution puts lifesaving overdose reversal medication directly into the hands of people who use drugs and their loved ones. Drug checking services, including fentanyl test strips, help people identify dangerous adulterants in their supply. Supervised consumption sites, operating in several countries and piloted in the United States, provide sterile environments with medical staff on hand to prevent fatal overdoses. Low-threshold MAT programs remove barriers to treatment by offering same-day starts, flexible scheduling, and minimal requirements for enrollment.
Harm reduction and abstinence are not competing philosophies — they are complementary approaches along a continuum of care. Many people who initially engage with harm reduction services eventually choose to pursue abstinence-based recovery. Research consistently shows that harm reduction programs serve as a critical bridge, connecting individuals to treatment they might never have accessed otherwise. Forcing a choice between the two creates a false dichotomy that costs lives.
MAT is itself a cornerstone harm reduction strategy. Buprenorphine and methadone maintenance programs dramatically reduce overdose deaths — studies show a 50% or greater reduction in all-cause mortality among patients receiving opioid agonist therapy. Beyond preventing fatal overdoses, MAT reduces HIV and hepatitis C transmission by decreasing injection drug use, lowers criminal activity and incarceration rates, and improves overall quality of life, housing stability, and employment outcomes. These benefits occur even when patients are not fully abstinent from all substances. By stabilizing brain chemistry and eliminating the desperate cycle of withdrawal and compulsive use, MAT gives people the stability they need to rebuild their lives. Facilities offering MAT as part of a harm reduction framework can be found through our opioid rehab directory.
FDA-Approved Medications: Detailed Guides
The U.S. Food and Drug Administration has approved several medications for the treatment of opioid and alcohol use disorders. Each works through a different mechanism and is suited to different clinical situations. Understanding the distinctions can help patients and families make informed decisions alongside their treatment providers. Explore our in-depth guides below.
Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist that completely blocks the euphoric and sedative effects of opioids, removing the incentive to use. It is available as a daily oral pill or as a monthly extended-release injection marketed as Vivitrol. Because naltrexone requires a full detox period before initiation — typically 7 to 14 days opioid-free — it is best suited for patients who have already completed withdrawal management. Naltrexone is also FDA-approved for alcohol use disorder, where it reduces cravings and heavy drinking days.
Learn more about Naltrexone →Buprenorphine (Suboxone)
Buprenorphine is a partial opioid agonist with a built-in ceiling effect, meaning its opioid effects plateau at moderate doses — significantly lowering the risk of respiratory depression and overdose. It is available as a sublingual film or tablet (commonly known by the brand name Suboxone, which also contains naloxone to deter misuse) and as a monthly subcutaneous injection (Sublocade). Buprenorphine can be prescribed in office-based settings by qualified providers, making it one of the most accessible MAT options. It effectively reduces cravings and withdrawal symptoms while carrying lower abuse potential than full agonists.
Learn more about Buprenorphine →Methadone
Methadone is a full opioid agonist with more than 60 years of clinical evidence supporting its effectiveness. Administered daily at certified Opioid Treatment Programs (OTPs), methadone eliminates withdrawal symptoms, suppresses cravings, and blocks the effects of other opioids when dosed correctly. It is considered the most effective option for individuals with severe opioid use disorder, particularly those who have not responded to other medications. The structured program participation required — including regular clinic visits, counseling, and drug screening — provides an additional layer of accountability and support.
Learn more about Methadone →Naloxone (Narcan)
Naloxone is an opioid antagonist used to rapidly reverse opioid overdoses. Available as a nasal spray (Narcan) and in injectable formulations, naloxone can restore normal breathing within minutes in a person experiencing respiratory depression from opioids. In 2023, Narcan nasal spray became available over the counter without a prescription, making it more accessible than ever. Every person who uses opioids, is prescribed high-dose opioid pain medication, or has a loved one at risk should keep naloxone on hand — it is safe, effective, and saves lives.
Learn more about Naloxone →MAT resources and information:
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