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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Medication-Assisted Treatment (MAT) Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.

Found 300 treatment centers offering medication-assisted treatment (mat) across the United States.

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Addiction Research and Treatment Inc

Addiction Research and Treatment Inc, situated in Richmond, CA, delivers extensive programs for individuals grappling with substance dependency, serving both adults and adolescents. Their offerings include outpatient detox, comprehensive substance use therapy, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The facility is dedicated to personalized recovery plans, employing therapeutic strategies like anger management, cognitive behavioral therapy, and motivational interviewing. Welcoming both men and women, the center prioritizes high-quality support and a nurturing atmosphere throughout the healing journey. For those requiring expert addiction care, this establishment provides customized solutions designed to meet diverse challenges within a professional and empathetic framework.

Addiction Resource Center LLC

Situated in Yuba City, CA, the Addiction Resource Center LLC provides a wide range of treatment options for substance use disorders. It offers intensive outpatient programs, standard outpatient services, and regular outpatient treatment tailored for different needs. The center employs various therapeutic methods, including 12-step facilitation, brief interventions, and cognitive behavioral therapy, targeting adult men, women, and active military members. With specific programs designed for both adults and young adults, it offers a personalized approach to care for all clients. The Addiction Resource Center LLC is committed to offering high-quality, impactful treatment resources to aid individuals in their recovery journey.

Addiction Services and Pharmacotherapy

Addiction Services and Pharmacotherapy, situated in Madison, WI, provides an extensive range of outpatient services aimed at tackling addiction. This center is dedicated to detoxification and treatment for substance use disorders, employing methods like motivational interviewing, relapse prevention strategies, and personalized counseling. It offers specialized programs for active-duty military personnel, as well as for adult men and women. Targeting both adult and young adult populations, the center delivers outpatient detoxification services alongside medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Committed to quality care, Addiction Services and Pharmacotherapy caters to both male and female clients in pursuit of recovery from addiction.

Addiction Services and Pharmacotherapy

Situated in Milwaukee, WI, "Addiction Services and Pharmacotherapy" delivers outpatient care for substance use disorders, featuring treatments like methadone, buprenorphine, and naltrexone. The center emphasizes therapeutic techniques such as cognitive behavioral therapy, motivational interviewing, and strategies for relapse prevention. It provides specialized services for adult men, adult women, and individuals affected by intimate partner or domestic violence, addressing a wide range of requirements. Catering to adults and young adults of all genders, the facility ensures high-quality care through customized treatment approaches. If you are in search of effective addiction support in a nurturing environment, this center presents in-depth programs designed to meet unique personal needs.

Addiction Services and Pharmacotherapy

Addiction Services and Pharmacotherapy in Kenosha, WI, provides outpatient substance abuse treatment including detoxification and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Their expertise lies in brief interventions, cognitive behavioral therapy, and motivational interviewing to confront addiction challenges. This center is dedicated to offering tailored support for adults and young adults across all genders, ensuring a high standard of care and assistance for individuals on their journey to recovery. Reach out to them for customized, successful treatment strategies aimed at long-term healing.

Addiction Services Council

Situated in Cincinnati, Ohio, the "Addiction Services Council" specializes in outpatient treatment for individuals of all ages dealing with substance use disorders alongside mental health challenges. This center employs proven methodologies such as 12-step facilitation, cognitive behavioral therapy, and brief intervention for regular outpatient services. Customized programs cater to the needs of teenagers, adult males, and adult females. Committed to providing high-quality care, this facility maintains a nurturing atmosphere for both men and women. For those in pursuit of thorough addiction care that also focuses on mental health, the Addiction Services Council is an excellent option for fostering long-term recovery.

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Addiction Services of Coastal Carolina, located in Kenansville, NC, provides outpatient programs for substance use for both adults and youth, as well as individuals facing dual mental health issues. The treatment options utilize evidence-based practices such as brief interventions, cognitive behavioral therapy, and motivational incentives through contingency management. This center serves both men and women, including clients dealing with legal matters. Prioritizing personalized care and high-quality support, the facility creates a nurturing atmosphere for individuals striving to conquer addiction and maintain long-term recovery.

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Addiction Services of Coastal Carolina, located in Jacksonville, NC, offers a wide range of treatment options for substance use disorders, including outpatient and intensive outpatient programs. The center is known for its expertise in brief intervention techniques, cognitive behavioral therapy, and the use of contingency management alongside motivational incentives. It features specialized programs for individuals dealing with both mental health issues and substance use problems, as well as services tailored for clients involved with the criminal justice system. Catering to adults as well as children and adolescents of all genders, the facility prioritizes high-quality care and evidence-informed strategies, making it a reputable option for those in need of effective addiction treatment within a nurturing atmosphere.

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Situated in Mount Pleasant, MI, the "Addiction Solutions Counseling Center" specializes in a variety of evidence-supported treatment options for individuals facing substance use challenges and concurrent mental health conditions, serving both adults and children. The center offers various treatment modalities, including intensive outpatient, outpatient, and standard outpatient services, employing techniques such as anger management, brief intervention, and cognitive-behavioral therapy. It also features specific programs designed for active military members, teenagers, and women. This facility caters to a wide demographic, including adults, seniors, and young adults of all genders, ensuring personalized care that effectively addresses individual needs. With a commitment to excellence and holistic support, the center is distinguished by its comprehensive range of treatment choices and specialized initiatives.

Addiction Specialists LLC
West Long Branch, NJ

Addiction Specialists LLC, situated in West Long Branch, New Jersey, delivers outpatient care for individuals struggling with substance use disorders. Their programs are designed for adults and young adults, employing proven therapeutic methods like 12-step facilitation, anger management techniques, and brief intervention strategies. They also offer specialized support groups for adult men, adult women, and older adults. Addiction Specialists LLC is dedicated to providing personalized treatment for both male and female clients, fostering a nurturing atmosphere to guide individuals toward lasting recovery.

Addiction Therapeutic Services

Nestled in Rancho Mirage, CA, Addiction Therapeutic Services is dedicated to providing a full spectrum of care for those facing addiction and accompanying mental health challenges. They offer essential detox services and personalized care strategies for adults managing severe mental health conditions, as well as children experiencing significant emotional distress. Their treatment offerings include robust intensive outpatient and day treatment options, ensuring a flexible approach to recovery. Employing methods like 12-step guidance and anger management techniques, their programs aim to foster enduring sobriety. Specialized support is available for active military personnel, teenagers, and adult men. Catering to individuals of all ages and genders, this center is committed to delivering exceptional care within a nurturing setting.

Addiction Treatment Center of NE

Situated in Brighton, MA, the Addiction Treatment Center of NE provides extensive outpatient services aimed at addressing substance use issues and co-occurring mental health conditions for both adults and children. The center features tailored care through outpatient treatments that include methadone/buprenorphine or naltrexone, facilitation of 12-step programs, anger management sessions, and brief therapeutic interventions. It also offers specialized programs for adult men and women, as well as those with experiences of intimate partner or domestic violence. Catering to individuals of all genders, this center emphasizes personalized treatment plans and evidence-based methodologies to foster enduring recovery and enhance overall wellness.

Addiction Treatment of Maryland

Addiction Treatment of Maryland in Dundalk, MD, delivers a complete suite of substance abuse recovery programs designed for adults and adolescents. Their offerings include intensive outpatient, standard outpatient, and day treatment, emphasizing 12-step support, emotional regulation, and rapid intervention strategies. Distinctive services are available for adult men, adult women, and survivors of domestic or intimate partner abuse. The center also provides transitional living accommodations, halfway house placements, and sober living environments. By offering distinct care pathways for male and female patients, this facility is committed to delivering effective treatment to guide individuals toward lasting sobriety.

Addiction Treatment Services

Addiction Treatment Services, situated in Traverse City, MI, provides an extensive range of services for individuals grappling with substance use disorders and mental health challenges. This center offers various treatment modalities, including intensive outpatient, outpatient, and day programs, incorporating methods like 12-step support, anger management, and short-term therapeutic strategies. Tailored programs are available for adolescents and both adult men and women, ensuring a broad spectrum of support for different demographics. Emphasizing personalized care, the center fosters a nurturing atmosphere for those pursuing healing from addiction and mental health difficulties.

Addiction Treatment Services

Situated in Traverse City, MI, Addiction Treatment Services is dedicated to providing focused care for adult males struggling with substance abuse issues. The center offers a variety of treatment options, including both long-term and short-term residential programs, as well as around-the-clock care customized to meet each person's specific requirements. Emphasizing techniques like 12-step facilitation, anger management, and brief intervention strategies, this facility is equipped to support individuals facing concurrent serious mental health challenges. Additionally, it provides specialized programs for those impacted by intimate partner violence, domestic abuse, and sexual trauma. Catering to adults, seniors, and young adults, the center's male-focused methodology fosters a nurturing atmosphere for clients pursuing thorough and empathetic addiction treatment.

Addiction Treatment Services

Traverse City's premier rehabilitation center offers complete assistance for those battling substance abuse and co-occurring psychological challenges. This facility delivers inpatient hospital detox and treatment designed for adults and young adults. Employing strategies such as 12-step facilitation, brief intervention, and community reinforcement with vouchers, the center customizes its methods to address each patient's specific requirements. Specialized services cater to adult men and women, as well as those affected by intimate partner violence. Dedicated to superior care and personalized recovery plans, the center strives to empower clients toward sustained healing.

Addiction Treatment Services

Addiction Treatment Services in Traverse City, MI, provides a complete spectrum of tailored programs for individuals facing substance use challenges. The center offers extended stay, short-term residential, and intermediate housing for adult women on their recovery journey. Employing methods like 12-step guidance, emotional regulation training, and quick intervention strategies, the center promotes a thorough treatment experience. Distinct programs are designed for adults with combined substance use and severe mental health conditions, as well as for children with emotional difficulties. Specialized support is extended to clients who have endured intimate partner abuse. Catering to adults, older adults, and young adults, this establishment is dedicated to delivering excellent care and personalized rehabilitation plans for its female clientele in a nurturing setting.

Addiction Treatment Strategies

At Addiction Treatment Strategies in Edwardsville, IL, we provide extensive support for adults and children grappling with substance use disorders and co-occurring mental health challenges. Our offerings include intensive outpatient programs, outpatient detoxification, and general outpatient care, all grounded in proven methods like cognitive behavioral therapy and contingency management. We are dedicated to a personalized approach, creating custom treatment plans for adults and seniors across all genders. Addiction Treatment Strategies is distinguished by its commitment to exceptional, individualized care, guiding each person toward lasting recovery.

Addiction Trt Servs International

Addiction Trt Servs International, located in Absecon, NJ, provides thorough and customized care for individuals facing addiction. The center focuses on addressing substance use disorders in adults and concurrent mental health or emotional challenges in children. Their therapeutic offerings include intensive outpatient and day treatment, incorporating elements like 12-step facilitation, anger management techniques, and brief intervention strategies. Addiction Trt Servs International designs specialized programs for adult men and women, as well as young adults, ensuring each person receives attention suited to their specific needs. The center is recognized for its gender-specific treatment approaches and dedication to fostering overall well-being and recovery. They employ proven methods to guide individuals toward lasting healing.

Addiction/Behavioral Csl Servs

Addiction/Behavioral Csl Servs, situated in Merrillville, IN, delivers all-encompassing care for individuals of all ages struggling with substance abuse. Their program offerings include intensive outpatient, outpatient, and standard outpatient services. The center employs proven therapeutic methods such as 12-step facilitation, anger management, and brief intervention, serving both male and female clients. They also feature tailored programs for active military members, adult men, and adult women, demonstrating a dedication to individualized support. Addiction/Behavioral Csl Servs is committed to providing high-quality recovery assistance.

Addictions and Family Counseling

Addictions and Family Counseling in Troutdale, OR, delivers extensive outpatient services for adults and seniors battling substance use disorders. The center adopts a tailored, individualized strategy to meet the specific requirements of every patient. Committed to high-quality care, this establishment welcomes both male and female individuals. Through a holistic treatment methodology, the program is designed to guide individuals toward lasting recovery. For those in need of assistance for themselves or someone they care about, this center offers a nurturing space to conquer addiction and begin anew.

Frequently Asked Questions

What is Medication-Assisted Treatment (MAT)?
MAT combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction treatment. Medications normalize brain chemistry, block euphoric effects of substances, relieve physiological cravings, and normalize body functions without negative effects of substance use. MAT is the gold standard for opioid and alcohol use disorders.
What medications are used in MAT?
For opioid use disorder: methadone, buprenorphine (Suboxone, Sublocade), and naltrexone (Vivitrol). For alcohol use disorder: naltrexone, acamprosate, and disulfiram. Each medication has unique benefits and considerations. A physician experienced in addiction medicine determines the most appropriate option based on individual circumstances, substance used, and treatment goals.
Is MAT just replacing one addiction with another?
No, this is a common misconception. MAT medications are prescribed at stable, therapeutic doses and don't produce euphoria when taken as directed. They're medicine, not substitution. MAT allows normal functioning, eliminates cravings, prevents withdrawal, dramatically reduces overdose risk, and enables engagement in therapy and rebuilding life. Research consistently shows MAT saves lives and improves outcomes.
How long does MAT last?
MAT duration varies by individual needs. Some people benefit from months of treatment, others years or indefinitely. There's no predetermined timeline. Research shows longer MAT duration improves outcomes and reduces overdose risk. Decisions about duration should be made collaboratively with healthcare providers based on stability, quality of life, and recovery goals, not arbitrary timelines.
Does insurance cover MAT?
Most health insurance plans cover MAT under mental health and substance use benefits. The Affordable Care Act and Mental Health Parity Act require coverage for addiction treatment including MAT. Coverage includes medications, office visits, counseling, and therapy. Contact your insurance provider or treatment center admissions to verify specific coverage and costs.

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.

MAT Medications for Opioid Use Disorder

Three FDA-approved medications treat opioid addiction:

  • Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
  • Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
  • Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.

MAT for Alcohol Use Disorder

FDA-approved medications for alcohol addiction:

  • Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
  • Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
  • Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking

Comprehensive Treatment Approach

MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.

Addressing Stigma and Misconceptions

MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.

Finding MAT Treatment

Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.

Harm Reduction and Medication-Assisted Treatment

Harm reduction is a public health philosophy that meets people where they are in their relationship with substance use. Rather than demanding abstinence as a precondition for support, harm reduction focuses on reducing the negative health, social, and economic consequences of drug use while keeping individuals alive, safe, and connected to care. This pragmatic approach recognizes that not everyone is ready or able to stop using substances immediately, and that incremental steps toward health are meaningful and worth supporting.

Harm reduction programs take many forms in communities across the country. Needle exchange and syringe service programs reduce the spread of HIV and hepatitis C among people who inject drugs. Naloxone (Narcan) distribution puts lifesaving overdose reversal medication directly into the hands of people who use drugs and their loved ones. Drug checking services, including fentanyl test strips, help people identify dangerous adulterants in their supply. Supervised consumption sites, operating in several countries and piloted in the United States, provide sterile environments with medical staff on hand to prevent fatal overdoses. Low-threshold MAT programs remove barriers to treatment by offering same-day starts, flexible scheduling, and minimal requirements for enrollment.

Harm reduction and abstinence are not competing philosophies — they are complementary approaches along a continuum of care. Many people who initially engage with harm reduction services eventually choose to pursue abstinence-based recovery. Research consistently shows that harm reduction programs serve as a critical bridge, connecting individuals to treatment they might never have accessed otherwise. Forcing a choice between the two creates a false dichotomy that costs lives.

MAT is itself a cornerstone harm reduction strategy. Buprenorphine and methadone maintenance programs dramatically reduce overdose deaths — studies show a 50% or greater reduction in all-cause mortality among patients receiving opioid agonist therapy. Beyond preventing fatal overdoses, MAT reduces HIV and hepatitis C transmission by decreasing injection drug use, lowers criminal activity and incarceration rates, and improves overall quality of life, housing stability, and employment outcomes. These benefits occur even when patients are not fully abstinent from all substances. By stabilizing brain chemistry and eliminating the desperate cycle of withdrawal and compulsive use, MAT gives people the stability they need to rebuild their lives. Facilities offering MAT as part of a harm reduction framework can be found through our opioid rehab directory.

FDA-Approved Medications: Detailed Guides

The U.S. Food and Drug Administration has approved several medications for the treatment of opioid and alcohol use disorders. Each works through a different mechanism and is suited to different clinical situations. Understanding the distinctions can help patients and families make informed decisions alongside their treatment providers. Explore our in-depth guides below.

Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist that completely blocks the euphoric and sedative effects of opioids, removing the incentive to use. It is available as a daily oral pill or as a monthly extended-release injection marketed as Vivitrol. Because naltrexone requires a full detox period before initiation — typically 7 to 14 days opioid-free — it is best suited for patients who have already completed withdrawal management. Naltrexone is also FDA-approved for alcohol use disorder, where it reduces cravings and heavy drinking days.

Learn more about Naltrexone →

Buprenorphine (Suboxone)

Buprenorphine is a partial opioid agonist with a built-in ceiling effect, meaning its opioid effects plateau at moderate doses — significantly lowering the risk of respiratory depression and overdose. It is available as a sublingual film or tablet (commonly known by the brand name Suboxone, which also contains naloxone to deter misuse) and as a monthly subcutaneous injection (Sublocade). Buprenorphine can be prescribed in office-based settings by qualified providers, making it one of the most accessible MAT options. It effectively reduces cravings and withdrawal symptoms while carrying lower abuse potential than full agonists.

Learn more about Buprenorphine →

Methadone

Methadone is a full opioid agonist with more than 60 years of clinical evidence supporting its effectiveness. Administered daily at certified Opioid Treatment Programs (OTPs), methadone eliminates withdrawal symptoms, suppresses cravings, and blocks the effects of other opioids when dosed correctly. It is considered the most effective option for individuals with severe opioid use disorder, particularly those who have not responded to other medications. The structured program participation required — including regular clinic visits, counseling, and drug screening — provides an additional layer of accountability and support.

Learn more about Methadone →

Naloxone (Narcan)

Naloxone is an opioid antagonist used to rapidly reverse opioid overdoses. Available as a nasal spray (Narcan) and in injectable formulations, naloxone can restore normal breathing within minutes in a person experiencing respiratory depression from opioids. In 2023, Narcan nasal spray became available over the counter without a prescription, making it more accessible than ever. Every person who uses opioids, is prescribed high-dose opioid pain medication, or has a loved one at risk should keep naloxone on hand — it is safe, effective, and saves lives.

Learn more about Naloxone →

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Browse medication-assisted treatment (mat) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)