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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Medication-Assisted Treatment (MAT) Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.

Found 300 treatment centers offering medication-assisted treatment (mat) across the United States.

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A Turning Point Family and

Situated in Baton Rouge, Louisiana, A Turning Point Family provides extensive addiction rehabilitation services for both adults and young adults. This center is dedicated to detoxification, treatment for substance use disorders, and managing co-occurring mental health issues. It offers a variety of treatment formats, including intensive outpatient programs, outpatient care, and day treatment. The facility employs strategies such as 12-step facilitation, anger management, and brief interventions. Specialized programs are designed for active-duty military personnel as well as for adult men and women. With a commitment to delivering exceptional care for all individuals, A Turning Point Family emphasizes the importance of addressing substance use alongside mental health challenges, aiming to support clients in achieving long-term recovery and enhanced well-being.

A Turning Point of Colorado Springs

A Turning Point of Colorado Springs, in Colorado Springs, CO, provides robust outpatient treatment options, including intensive, regular, and general outpatient care for addiction. Their specialized services encompass 12-step program integration, anger management techniques, and brief intervention strategies. This facility is dedicated to offering tailored care for adults, adolescents, and young adults of all genders. Their distinctive approach involves crafting individualized treatment plans to meet the unique requirements of each person. For those in search of empathetic and thorough addiction treatment, this center delivers excellent services to aid in their path to recovery.

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Thousand Oaks, CA

Wildwood Recovery in Thousand Oaks, CA, provides extensive addiction rehabilitation for adults and young adults. This center delivers hospital-based inpatient detox and care for substance abuse issues and accompanying mental health challenges. Emphasizing 12-step guidance, emotional regulation, and concise therapeutic strategies, Wildwood Recovery features distinct tracks for adult men, adult women, and individuals with dual diagnoses. Customizing treatment to address individual requirements, the program guarantees high-quality support and care for all clients embarking on their path to sobriety.

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Thousand Oaks, CA

Wildwood Recovery IOP, located in Thousand Oaks, California, provides intensive outpatient and outpatient care for individuals dealing with substance use issues and co-occurring mental health conditions. The center emphasizes approaches such as 12-step facilitation, anger management, and brief intervention strategies. It offers tailored programs designed for adult men, women, and those with dual diagnoses. Serving both adults and young adults, this facility ensures that care is personalized to meet specific needs. What sets Wildwood Recovery IOP apart is its extensive range of treatment options and dedication to tackling the intricate nature of addiction and mental health concerns.

A and D Counseling LLC
Westminster, CO

A and D Counseling LLC, situated in Westminster, Colorado, provides an extensive array of substance abuse treatment services. This center offers intensive outpatient programs, outpatient care, and standard outpatient options. Employing methods like anger management, brief intervention techniques, and cognitive behavioral therapy, the facility addresses diverse patient requirements. Specific programs are designed for active duty military members, young people, and adult males. With an emphasis on care for both adults and children/adolescents of all genders, A and D Counseling LLC is dedicated to providing personalized treatment. Discover exceptional addiction recovery services in a welcoming and supportive setting at this respected rehabilitation center.

A and D Counseling LLC

A and D Counseling LLC in Aurora, CO, delivers targeted outpatient services for individuals of all ages struggling with substance use. Employing methods like anger management, motivational interviewing, and cognitive behavioral therapy, they provide personalized care for active military members, adult males, and teenagers. The center emphasizes creating customized recovery strategies for both male and female patients. A and D Counseling LLC is distinguished by its thorough programs, developed to meet the specific requirements of different age demographics and genders. Patients can anticipate superior support and guidance on their path to wellness at this establishment.

A and M Recovery LLC
Springfield, MO

A and M Recovery LLC located in Springfield, MO, provides an extensive array of substance abuse treatment options designed to address the distinct requirements of adult men and women. The center offers various treatment levels including intensive outpatient and outpatient programs. Emphasizing cognitive behavioral therapy, anger management, and brief intervention methods, the facility guarantees personalized support for clients in need of assistance. Additionally, specialized programs are available for those who have faced intimate partner or domestic violence. Catering to both adults and young adults from all genders, A and M Recovery LLC is committed to delivering exceptional rehabilitation services to foster enduring recovery.

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AA and Associates of Kentucky, situated in Carrollton, KY, delivers a full spectrum of substance use recovery services for adults and adolescents. They offer intensive outpatient, outpatient, and standard outpatient treatment modalities. Employing methods such as 12-step integration, brief intervention strategies, and cognitive behavioral therapy, this establishment serves active military personnel, adult males, and adult females. Their tailored programs for different genders and age demographics guarantee customized assistance and care for those pursuing recovery. Discover excellent treatment and personal recovery journeys at this respected addiction treatment facility.

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Belleville, IL

AAA DUI Services Inc. in Belleville, IL, provides outpatient substance abuse counseling designed around each client's specific requirements. This center serves adults and older adults of all genders with its regular outpatient programming. Employing methods like 12-step encouragement, concise intervention techniques, and cognitive behavioral therapy, the program is adapted to the distinct circumstances of every individual. The facility's focused interventions promise a premium experience for those pursuing recovery from addiction. For those in search of a treatment facility that prioritizes tailored support and employs proven therapeutic techniques, AAA DUI Services Inc. may be an excellent option.

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Laredo, TX

Situated in Laredo, TX, AAMA Inc specializes in outpatient treatment for substance use disorders with an emphasis on detox and the administration of methadone/buprenorphine or naltrexone therapies. The center delivers consistent outpatient services through methods like anger management, brief intervention, and cognitive behavioral therapy. AAMA Inc serves adult men and women, including individuals who've encountered intimate partner or domestic violence. Aimed at both adults and young adults, the facility provides tailored care for both genders. With an emphasis on personalized support and high-quality services, AAMA Inc is a well-rounded rehabilitation center that addresses diverse addiction challenges.

ABBCON Counseling Inc

ABBCON Counseling Inc located in Mattoon, IL, specializes in outpatient services for substance use disorders. The center employs a range of methods, including anger management, brief intervention, and cognitive behavioral therapy, to deliver consistent outpatient care. With an emphasis on personalized treatment, this facility supports both adults and youth of all genders. ABBCON Counseling Inc differentiates itself through customized programs that meet the specific requirements of each individual. Its high standard of care and variety of treatment strategies make this center an essential option for individuals pursuing tailored addiction recovery solutions.

ABC Recovery Center Inc

ABC Recovery Center Inc located in Indio, CA, specializes in extensive substance abuse treatment and provides transitional living arrangements, including sober living homes and halfway houses. This facility offers intensive outpatient services designed to foster a nurturing atmosphere, and incorporates methods such as 12-step programs, anger management, and cognitive behavioral techniques. There are specific programs designed for adult men and women, with additional services for those affected by domestic violence or intimate partner violence. Catering to both adults and young adults of all genders, this center prioritizes personalized care, establishing itself as a crucial support system for individuals pursuing effective pathways to recovery from addiction.

ABC Recovery Center Inc

At ABC Recovery Center Inc, located in Indio, CA, we provide extensive support for those battling addiction. Our services encompass the full spectrum of care, from initial detox to ongoing substance use treatment and stable transitional housing. Residents benefit from a secure, long-term residential environment offering continuous 24-hour assistance. We utilize proven therapeutic methods, including cognitive behavioral therapy and 12-step program integration. Our tailored programs are designed for adult men and women, with special considerations for individuals who have faced intimate partner violence. We also address anger management and offer highly personalized care plans for adults and young adults of all gender identities as they embark on their recovery journey. ABC Recovery Center Inc is dedicated to delivering exceptional, customized treatment to facilitate enduring sobriety.

ABC Recovery Center Inc

ABC Recovery Center Inc, located in Indio, CA, provides a full spectrum of substance abuse treatment options. This establishment is particularly adept at long-term residential rehabilitation and inpatient detox for adult women. Their approach emphasizes 12-step facilitation, anger management, and cognitive-behavioral therapy, designed for individuals facing co-occurring mental health and substance use issues, including those living with HIV or AIDS. Catering to a diverse age range from young adults to seniors, the center fosters a nurturing setting for women to begin their path to wellness. Known for its dedication to high-quality, evidence-based care, ABC Recovery Center Inc stands as a reliable choice for effective addiction treatment.

ABC Sober Living LLC

ABC Sober Living LLC, located in San Diego, CA, specializes in providing extensive treatment for substance use as well as transitional housing specifically for adult women. The center employs intensive outpatient services that leverage proven methods, including 12-step facilitation, cognitive behavioral therapy, and contingency management. This program is particularly beneficial for individuals who have faced trauma or sexual abuse. With an emphasis on females spanning various age groups, including adults, seniors, and young adults, the center guarantees personalized attention in a nurturing atmosphere. ABC Sober Living LLC is recognized for its dedication to high-quality care and customized treatment plans that meet the distinct requirements of each person on their path to recovery.

ABC Therapy Inc
Las Vegas, NV

Located in Las Vegas, NV, ABC Therapy Inc provides a wide range of rehabilitation services aimed at supporting individuals facing challenges related to substance abuse and associated mental health disorders. Their customized programs encompass intensive outpatient treatment as well as both standard outpatient and regular outpatient care. The center emphasizes 12-step support, anger management techniques, and brief intervention strategies. They also offer specialized programs designed for active duty military personnel, teenagers, and adult males. Committed to creating a nurturing atmosphere, ABC Therapy Inc serves adults and youth of every gender, focusing on delivering personalized, high-quality care that promotes enduring sobriety and mental well-being.

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Bloomington, IL

Located in Bloomington, IL, ABC Unlimited Inc specializes in outpatient treatment for substance use disorders, catering to both adult men and women, including individuals impacted by intimate partner violence. The center emphasizes a combination of 12-step facilitation, anger management strategies, and brief intervention techniques, all designed to create a customized experience for those pursuing recovery. Programs are specifically developed for adult men, adult women, and clients with backgrounds in intimate partner violence. ABC Unlimited Inc is committed to delivering high-quality care in a nurturing atmosphere for adults and young adults of all genders. If you are in search of tailored outpatient therapy in Bloomington, this facility might be the perfect fit for your path to recovery.

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Elberton, GA

ABHS, situated in Elberton, GA, provides a complete spectrum of addiction recovery services for both adults and young people. Their offerings include detoxification, drug and alcohol dependency treatment, and sober living accommodations within a nurturing atmosphere. This facility, which features intensive outpatient programs and cognitive behavioral therapy, excels in anger control and short-term intervention strategies. ABHS serves adult men and women, along with individuals who have faced trauma. By customizing programs for various age demographics and genders, the center guarantees individualized support for everyone pursuing sobriety. Rely on ABHS for excellent service and successful treatment approaches in your path to recovery.

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ABODE Treatment Inc located in Dallas, TX, provides a wide range of substance abuse treatment options that include intensive outpatient, outpatient, and standard outpatient programs. The center employs proven methods like 12-step facilitation, cognitive behavioral therapy, and motivational incentives/contingency management to create personalized treatment plans for adults and young adults of all genders. With specialized programs for military personnel, men, and women, ABODE Treatment Inc is dedicated to offering individualized assistance to each client. Its emphasis on high-quality care and a variety of therapeutic options positions it as a reliable resource for those in need of effective rehabilitation in the Dallas region.

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Situated in Abilene, TX, ABODE Treatment Inc specializes in extensive rehabilitation services for both adults and young adults struggling with substance use issues. The facility offers various treatment options, including intensive outpatient, outpatient, and standard outpatient programs. By implementing proven methodologies like 12-step facilitation, cognitive behavioral therapy, and contingency management, it serves adult men, women, and members of the military. With an emphasis on tailored care, ABODE Treatment Inc is dedicated to providing effective support to individuals aiming to conquer addiction and secure a sustainable recovery.

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ABRAXAS Youth and Family Services, located in Chicago, IL, delivers a complete range of therapeutic services addressing addiction, chemical dependency, and co-occurring psychological conditions. They provide round-the-clock inpatient hospital care for adults and young adults, with specialized interventions like 12-step program support and anger management techniques. ABRAXAS also supports individuals affected by domestic violence and offers distinct, personalized programs for adult men and women. The center's unique strength lies in its integrated strategy, simultaneously treating substance abuse and mental health challenges for a more complete recovery journey.

Frequently Asked Questions

What is Medication-Assisted Treatment (MAT)?
MAT combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction treatment. Medications normalize brain chemistry, block euphoric effects of substances, relieve physiological cravings, and normalize body functions without negative effects of substance use. MAT is the gold standard for opioid and alcohol use disorders.
What medications are used in MAT?
For opioid use disorder: methadone, buprenorphine (Suboxone, Sublocade), and naltrexone (Vivitrol). For alcohol use disorder: naltrexone, acamprosate, and disulfiram. Each medication has unique benefits and considerations. A physician experienced in addiction medicine determines the most appropriate option based on individual circumstances, substance used, and treatment goals.
Is MAT just replacing one addiction with another?
No, this is a common misconception. MAT medications are prescribed at stable, therapeutic doses and don't produce euphoria when taken as directed. They're medicine, not substitution. MAT allows normal functioning, eliminates cravings, prevents withdrawal, dramatically reduces overdose risk, and enables engagement in therapy and rebuilding life. Research consistently shows MAT saves lives and improves outcomes.
How long does MAT last?
MAT duration varies by individual needs. Some people benefit from months of treatment, others years or indefinitely. There's no predetermined timeline. Research shows longer MAT duration improves outcomes and reduces overdose risk. Decisions about duration should be made collaboratively with healthcare providers based on stability, quality of life, and recovery goals, not arbitrary timelines.
Does insurance cover MAT?
Most health insurance plans cover MAT under mental health and substance use benefits. The Affordable Care Act and Mental Health Parity Act require coverage for addiction treatment including MAT. Coverage includes medications, office visits, counseling, and therapy. Contact your insurance provider or treatment center admissions to verify specific coverage and costs.

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.

MAT Medications for Opioid Use Disorder

Three FDA-approved medications treat opioid addiction:

  • Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
  • Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
  • Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.

MAT for Alcohol Use Disorder

FDA-approved medications for alcohol addiction:

  • Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
  • Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
  • Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking

Comprehensive Treatment Approach

MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.

Addressing Stigma and Misconceptions

MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.

Finding MAT Treatment

Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.

Harm Reduction and Medication-Assisted Treatment

Harm reduction is a public health philosophy that meets people where they are in their relationship with substance use. Rather than demanding abstinence as a precondition for support, harm reduction focuses on reducing the negative health, social, and economic consequences of drug use while keeping individuals alive, safe, and connected to care. This pragmatic approach recognizes that not everyone is ready or able to stop using substances immediately, and that incremental steps toward health are meaningful and worth supporting.

Harm reduction programs take many forms in communities across the country. Needle exchange and syringe service programs reduce the spread of HIV and hepatitis C among people who inject drugs. Naloxone (Narcan) distribution puts lifesaving overdose reversal medication directly into the hands of people who use drugs and their loved ones. Drug checking services, including fentanyl test strips, help people identify dangerous adulterants in their supply. Supervised consumption sites, operating in several countries and piloted in the United States, provide sterile environments with medical staff on hand to prevent fatal overdoses. Low-threshold MAT programs remove barriers to treatment by offering same-day starts, flexible scheduling, and minimal requirements for enrollment.

Harm reduction and abstinence are not competing philosophies — they are complementary approaches along a continuum of care. Many people who initially engage with harm reduction services eventually choose to pursue abstinence-based recovery. Research consistently shows that harm reduction programs serve as a critical bridge, connecting individuals to treatment they might never have accessed otherwise. Forcing a choice between the two creates a false dichotomy that costs lives.

MAT is itself a cornerstone harm reduction strategy. Buprenorphine and methadone maintenance programs dramatically reduce overdose deaths — studies show a 50% or greater reduction in all-cause mortality among patients receiving opioid agonist therapy. Beyond preventing fatal overdoses, MAT reduces HIV and hepatitis C transmission by decreasing injection drug use, lowers criminal activity and incarceration rates, and improves overall quality of life, housing stability, and employment outcomes. These benefits occur even when patients are not fully abstinent from all substances. By stabilizing brain chemistry and eliminating the desperate cycle of withdrawal and compulsive use, MAT gives people the stability they need to rebuild their lives. Facilities offering MAT as part of a harm reduction framework can be found through our opioid rehab directory.

FDA-Approved Medications: Detailed Guides

The U.S. Food and Drug Administration has approved several medications for the treatment of opioid and alcohol use disorders. Each works through a different mechanism and is suited to different clinical situations. Understanding the distinctions can help patients and families make informed decisions alongside their treatment providers. Explore our in-depth guides below.

Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist that completely blocks the euphoric and sedative effects of opioids, removing the incentive to use. It is available as a daily oral pill or as a monthly extended-release injection marketed as Vivitrol. Because naltrexone requires a full detox period before initiation — typically 7 to 14 days opioid-free — it is best suited for patients who have already completed withdrawal management. Naltrexone is also FDA-approved for alcohol use disorder, where it reduces cravings and heavy drinking days.

Learn more about Naltrexone →

Buprenorphine (Suboxone)

Buprenorphine is a partial opioid agonist with a built-in ceiling effect, meaning its opioid effects plateau at moderate doses — significantly lowering the risk of respiratory depression and overdose. It is available as a sublingual film or tablet (commonly known by the brand name Suboxone, which also contains naloxone to deter misuse) and as a monthly subcutaneous injection (Sublocade). Buprenorphine can be prescribed in office-based settings by qualified providers, making it one of the most accessible MAT options. It effectively reduces cravings and withdrawal symptoms while carrying lower abuse potential than full agonists.

Learn more about Buprenorphine →

Methadone

Methadone is a full opioid agonist with more than 60 years of clinical evidence supporting its effectiveness. Administered daily at certified Opioid Treatment Programs (OTPs), methadone eliminates withdrawal symptoms, suppresses cravings, and blocks the effects of other opioids when dosed correctly. It is considered the most effective option for individuals with severe opioid use disorder, particularly those who have not responded to other medications. The structured program participation required — including regular clinic visits, counseling, and drug screening — provides an additional layer of accountability and support.

Learn more about Methadone →

Naloxone (Narcan)

Naloxone is an opioid antagonist used to rapidly reverse opioid overdoses. Available as a nasal spray (Narcan) and in injectable formulations, naloxone can restore normal breathing within minutes in a person experiencing respiratory depression from opioids. In 2023, Narcan nasal spray became available over the counter without a prescription, making it more accessible than ever. Every person who uses opioids, is prescribed high-dose opioid pain medication, or has a loved one at risk should keep naloxone on hand — it is safe, effective, and saves lives.

Learn more about Naloxone →

MAT resources and information:

Find Medication-Assisted Treatment (MAT) by State

Browse medication-assisted treatment (mat) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)