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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Medication-Assisted Treatment (MAT) Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.

Found 300 treatment centers offering medication-assisted treatment (mat) across the United States.

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Chicago, IL

In Chicago, Illinois, "A Safe Haven" provides extensive services for substance use disorders, including transitional accommodations and supportive sober living. The center offers a spectrum of care, from intensive outpatient to regular outpatient programs, all individualized for each client. Their therapeutic framework incorporates proven methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy. "A Safe Haven" is dedicated to assisting adult males, active service members, survivors of domestic abuse, and adults across the age spectrum. Committed to high-quality treatment and tailored guidance, the facility supports individuals of any gender embarking on their path to recovery in a secure and encouraging setting.

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Meridian, MS

"A Second Chance," situated in Meridian, MS, provides outpatient addiction treatment for adults. This center is particularly adept at assisting individuals impacted by domestic or intimate partner violence. Employing proven therapeutic methods such as 12-step facilitation, cognitive behavioral therapy, and the Matrix Model, the program is designed for adults and young adults pursuing effective recovery. "A Second Chance" is committed to offering personalized support and a secure, encouraging setting for those starting their path to sobriety.

A Time to Rise Csl and Wellness LLC

A Time to Rise Csl and Wellness LLC in Brewer, ME, specializes in extensive substance abuse recovery services for adults and adolescents, including those facing dual diagnoses. Their flexible treatment options range from intensive outpatient to standard outpatient, all personalized for each individual's journey. Employing proven methods like anger management, brief intervention, and cognitive behavioral therapy, they deliver exceptional care to all genders. Their distinctiveness lies in dedicated programs for co-occurring conditions, empowering clients toward sustained sobriety and enhanced wellness.

A Turning Point Family and

Situated in Baton Rouge, Louisiana, A Turning Point Family provides extensive addiction rehabilitation services for both adults and young adults. This center is dedicated to detoxification, treatment for substance use disorders, and managing co-occurring mental health issues. It offers a variety of treatment formats, including intensive outpatient programs, outpatient care, and day treatment. The facility employs strategies such as 12-step facilitation, anger management, and brief interventions. Specialized programs are designed for active-duty military personnel as well as for adult men and women. With a commitment to delivering exceptional care for all individuals, A Turning Point Family emphasizes the importance of addressing substance use alongside mental health challenges, aiming to support clients in achieving long-term recovery and enhanced well-being.

A Turning Point of Colorado Springs

A Turning Point of Colorado Springs, in Colorado Springs, CO, provides robust outpatient treatment options, including intensive, regular, and general outpatient care for addiction. Their specialized services encompass 12-step program integration, anger management techniques, and brief intervention strategies. This facility is dedicated to offering tailored care for adults, adolescents, and young adults of all genders. Their distinctive approach involves crafting individualized treatment plans to meet the unique requirements of each person. For those in search of empathetic and thorough addiction treatment, this center delivers excellent services to aid in their path to recovery.

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Thousand Oaks, CA

Wildwood Recovery in Thousand Oaks, CA, provides extensive addiction rehabilitation for adults and young adults. This center delivers hospital-based inpatient detox and care for substance abuse issues and accompanying mental health challenges. Emphasizing 12-step guidance, emotional regulation, and concise therapeutic strategies, Wildwood Recovery features distinct tracks for adult men, adult women, and individuals with dual diagnoses. Customizing treatment to address individual requirements, the program guarantees high-quality support and care for all clients embarking on their path to sobriety.

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Thousand Oaks, CA

Wildwood Recovery IOP, located in Thousand Oaks, California, provides intensive outpatient and outpatient care for individuals dealing with substance use issues and co-occurring mental health conditions. The center emphasizes approaches such as 12-step facilitation, anger management, and brief intervention strategies. It offers tailored programs designed for adult men, women, and those with dual diagnoses. Serving both adults and young adults, this facility ensures that care is personalized to meet specific needs. What sets Wildwood Recovery IOP apart is its extensive range of treatment options and dedication to tackling the intricate nature of addiction and mental health concerns.

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AA and Associates of Kentucky, situated in Carrollton, KY, delivers a full spectrum of substance use recovery services for adults and adolescents. They offer intensive outpatient, outpatient, and standard outpatient treatment modalities. Employing methods such as 12-step integration, brief intervention strategies, and cognitive behavioral therapy, this establishment serves active military personnel, adult males, and adult females. Their tailored programs for different genders and age demographics guarantee customized assistance and care for those pursuing recovery. Discover excellent treatment and personal recovery journeys at this respected addiction treatment facility.

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Belleville, IL

AAA DUI Services Inc. in Belleville, IL, provides outpatient substance abuse counseling designed around each client's specific requirements. This center serves adults and older adults of all genders with its regular outpatient programming. Employing methods like 12-step encouragement, concise intervention techniques, and cognitive behavioral therapy, the program is adapted to the distinct circumstances of every individual. The facility's focused interventions promise a premium experience for those pursuing recovery from addiction. For those in search of a treatment facility that prioritizes tailored support and employs proven therapeutic techniques, AAA DUI Services Inc. may be an excellent option.

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Laredo, TX

Situated in Laredo, TX, AAMA Inc specializes in outpatient treatment for substance use disorders with an emphasis on detox and the administration of methadone/buprenorphine or naltrexone therapies. The center delivers consistent outpatient services through methods like anger management, brief intervention, and cognitive behavioral therapy. AAMA Inc serves adult men and women, including individuals who've encountered intimate partner or domestic violence. Aimed at both adults and young adults, the facility provides tailored care for both genders. With an emphasis on personalized support and high-quality services, AAMA Inc is a well-rounded rehabilitation center that addresses diverse addiction challenges.

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Situated in Rochester, MI, Abaris Behavioral Health specializes in providing tailored substance use treatment for adults and seniors through its outpatient and standard outpatient programs. The facility employs various methods including anger management, brief intervention, and cognitive behavioral therapy, ensuring that care is customized to meet the specific needs of every client. Abaris Behavioral Health distinguishes itself through its commitment to creating individualized treatment plans that cater to the distinct challenges faced by each person. Offering services for both men and women, the center promotes a holistic and inclusive recovery process. Discover exceptional care and guidance on your path to recovery at this esteemed rehabilitation center.

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Abaris Behavioral Health, located in Novi, MI, specializes in outpatient services for substance use disorders, catering to both adults and seniors. The center emphasizes personalized care, offering programs such as anger management, brief interventions, and cognitive behavioral therapy. Its tailored services accommodate both men and women. Abaris Behavioral Health is recognized for its dedication to delivering high-quality care and custom treatment plans. For those in search of effective addiction recovery solutions in a supportive setting, this center offers an extensive array of services designed to assist in the recovery process.

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Abaris Behavioral Health in Utica, MI, specializes in personalized outpatient programs for adults and seniors dealing with substance use issues. They employ various therapeutic techniques, including anger management, brief intervention, and cognitive behavioral therapy, to craft unique treatment plans. Abaris Behavioral Health is dedicated to delivering a tailored and thorough recovery journey for every individual. The center welcomes both men and women, fostering a welcoming atmosphere for those pursuing effective addiction treatment in the Utica community.

ABBCON Counseling Inc

ABBCON Counseling Inc located in Mattoon, IL, specializes in outpatient services for substance use disorders. The center employs a range of methods, including anger management, brief intervention, and cognitive behavioral therapy, to deliver consistent outpatient care. With an emphasis on personalized treatment, this facility supports both adults and youth of all genders. ABBCON Counseling Inc differentiates itself through customized programs that meet the specific requirements of each individual. Its high standard of care and variety of treatment strategies make this center an essential option for individuals pursuing tailored addiction recovery solutions.

Abbey LLC
Bettendorf, IA

Situated in Bettendorf, IA, Abbey LLC delivers a wide range of addiction recovery services for both adults and young adults. The facility focuses on detoxification, treatment for substance use disorders, and offers tailored care for those with simultaneous mental health concerns. To ensure that clients receive personalized support, Abbey LLC provides various treatment modalities, including intensive outpatient, long-term residential, and outpatient programs. The center employs evidence-based techniques, such as cognitive behavioral therapy and 12-step facilitation, as well as specialized programs designed for adult men, women, and individuals with dual diagnoses. With an emphasis on high-quality care and customized treatment plans, Abbey LLC is committed to assisting clients throughout their recovery journey.

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Orchard Park, NY

Situated in Orchard Park, NY, Abbott stands out as a leading rehab facility that specializes in outpatient care for substance use disorders and co-occurring issues in both adults and children. The center offers various treatment options, which include outpatient therapy utilizing methadone, buprenorphine, or naltrexone. Emphasizing evidence-based methods such as cognitive behavioral therapy and anger management, Abbott serves active-duty military members, teenagers, and adult males. By providing tailored care for both men and women, Abbott is dedicated to helping individuals navigate their recovery from addiction and mental health difficulties.

ABC Recovery Center Inc

ABC Recovery Center Inc located in Indio, CA, specializes in extensive substance abuse treatment and provides transitional living arrangements, including sober living homes and halfway houses. This facility offers intensive outpatient services designed to foster a nurturing atmosphere, and incorporates methods such as 12-step programs, anger management, and cognitive behavioral techniques. There are specific programs designed for adult men and women, with additional services for those affected by domestic violence or intimate partner violence. Catering to both adults and young adults of all genders, this center prioritizes personalized care, establishing itself as a crucial support system for individuals pursuing effective pathways to recovery from addiction.

ABC Recovery Center Inc

At ABC Recovery Center Inc, located in Indio, CA, we provide extensive support for those battling addiction. Our services encompass the full spectrum of care, from initial detox to ongoing substance use treatment and stable transitional housing. Residents benefit from a secure, long-term residential environment offering continuous 24-hour assistance. We utilize proven therapeutic methods, including cognitive behavioral therapy and 12-step program integration. Our tailored programs are designed for adult men and women, with special considerations for individuals who have faced intimate partner violence. We also address anger management and offer highly personalized care plans for adults and young adults of all gender identities as they embark on their recovery journey. ABC Recovery Center Inc is dedicated to delivering exceptional, customized treatment to facilitate enduring sobriety.

ABC Recovery Center Inc

ABC Recovery Center Inc, located in Indio, CA, provides a full spectrum of substance abuse treatment options. This establishment is particularly adept at long-term residential rehabilitation and inpatient detox for adult women. Their approach emphasizes 12-step facilitation, anger management, and cognitive-behavioral therapy, designed for individuals facing co-occurring mental health and substance use issues, including those living with HIV or AIDS. Catering to a diverse age range from young adults to seniors, the center fosters a nurturing setting for women to begin their path to wellness. Known for its dedication to high-quality, evidence-based care, ABC Recovery Center Inc stands as a reliable choice for effective addiction treatment.

ABC Sober Living LLC

ABC Sober Living LLC, located in San Diego, CA, specializes in providing extensive treatment for substance use as well as transitional housing specifically for adult women. The center employs intensive outpatient services that leverage proven methods, including 12-step facilitation, cognitive behavioral therapy, and contingency management. This program is particularly beneficial for individuals who have faced trauma or sexual abuse. With an emphasis on females spanning various age groups, including adults, seniors, and young adults, the center guarantees personalized attention in a nurturing atmosphere. ABC Sober Living LLC is recognized for its dedication to high-quality care and customized treatment plans that meet the distinct requirements of each person on their path to recovery.

ABC Therapy Inc
Las Vegas, NV

Located in Las Vegas, NV, ABC Therapy Inc provides a wide range of rehabilitation services aimed at supporting individuals facing challenges related to substance abuse and associated mental health disorders. Their customized programs encompass intensive outpatient treatment as well as both standard outpatient and regular outpatient care. The center emphasizes 12-step support, anger management techniques, and brief intervention strategies. They also offer specialized programs designed for active duty military personnel, teenagers, and adult males. Committed to creating a nurturing atmosphere, ABC Therapy Inc serves adults and youth of every gender, focusing on delivering personalized, high-quality care that promotes enduring sobriety and mental well-being.

Frequently Asked Questions

What is Medication-Assisted Treatment (MAT)?
MAT combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction treatment. Medications normalize brain chemistry, block euphoric effects of substances, relieve physiological cravings, and normalize body functions without negative effects of substance use. MAT is the gold standard for opioid and alcohol use disorders.
What medications are used in MAT?
For opioid use disorder: methadone, buprenorphine (Suboxone, Sublocade), and naltrexone (Vivitrol). For alcohol use disorder: naltrexone, acamprosate, and disulfiram. Each medication has unique benefits and considerations. A physician experienced in addiction medicine determines the most appropriate option based on individual circumstances, substance used, and treatment goals.
Is MAT just replacing one addiction with another?
No, this is a common misconception. MAT medications are prescribed at stable, therapeutic doses and don't produce euphoria when taken as directed. They're medicine, not substitution. MAT allows normal functioning, eliminates cravings, prevents withdrawal, dramatically reduces overdose risk, and enables engagement in therapy and rebuilding life. Research consistently shows MAT saves lives and improves outcomes.
How long does MAT last?
MAT duration varies by individual needs. Some people benefit from months of treatment, others years or indefinitely. There's no predetermined timeline. Research shows longer MAT duration improves outcomes and reduces overdose risk. Decisions about duration should be made collaboratively with healthcare providers based on stability, quality of life, and recovery goals, not arbitrary timelines.
Does insurance cover MAT?
Most health insurance plans cover MAT under mental health and substance use benefits. The Affordable Care Act and Mental Health Parity Act require coverage for addiction treatment including MAT. Coverage includes medications, office visits, counseling, and therapy. Contact your insurance provider or treatment center admissions to verify specific coverage and costs.

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.

MAT Medications for Opioid Use Disorder

Three FDA-approved medications treat opioid addiction:

  • Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
  • Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
  • Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.

MAT for Alcohol Use Disorder

FDA-approved medications for alcohol addiction:

  • Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
  • Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
  • Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking

Comprehensive Treatment Approach

MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.

Addressing Stigma and Misconceptions

MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.

Finding MAT Treatment

Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.

Harm Reduction and Medication-Assisted Treatment

Harm reduction is a public health philosophy that meets people where they are in their relationship with substance use. Rather than demanding abstinence as a precondition for support, harm reduction focuses on reducing the negative health, social, and economic consequences of drug use while keeping individuals alive, safe, and connected to care. This pragmatic approach recognizes that not everyone is ready or able to stop using substances immediately, and that incremental steps toward health are meaningful and worth supporting.

Harm reduction programs take many forms in communities across the country. Needle exchange and syringe service programs reduce the spread of HIV and hepatitis C among people who inject drugs. Naloxone (Narcan) distribution puts lifesaving overdose reversal medication directly into the hands of people who use drugs and their loved ones. Drug checking services, including fentanyl test strips, help people identify dangerous adulterants in their supply. Supervised consumption sites, operating in several countries and piloted in the United States, provide sterile environments with medical staff on hand to prevent fatal overdoses. Low-threshold MAT programs remove barriers to treatment by offering same-day starts, flexible scheduling, and minimal requirements for enrollment.

Harm reduction and abstinence are not competing philosophies — they are complementary approaches along a continuum of care. Many people who initially engage with harm reduction services eventually choose to pursue abstinence-based recovery. Research consistently shows that harm reduction programs serve as a critical bridge, connecting individuals to treatment they might never have accessed otherwise. Forcing a choice between the two creates a false dichotomy that costs lives.

MAT is itself a cornerstone harm reduction strategy. Buprenorphine and methadone maintenance programs dramatically reduce overdose deaths — studies show a 50% or greater reduction in all-cause mortality among patients receiving opioid agonist therapy. Beyond preventing fatal overdoses, MAT reduces HIV and hepatitis C transmission by decreasing injection drug use, lowers criminal activity and incarceration rates, and improves overall quality of life, housing stability, and employment outcomes. These benefits occur even when patients are not fully abstinent from all substances. By stabilizing brain chemistry and eliminating the desperate cycle of withdrawal and compulsive use, MAT gives people the stability they need to rebuild their lives. Facilities offering MAT as part of a harm reduction framework can be found through our opioid rehab directory.

FDA-Approved Medications: Detailed Guides

The U.S. Food and Drug Administration has approved several medications for the treatment of opioid and alcohol use disorders. Each works through a different mechanism and is suited to different clinical situations. Understanding the distinctions can help patients and families make informed decisions alongside their treatment providers. Explore our in-depth guides below.

Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist that completely blocks the euphoric and sedative effects of opioids, removing the incentive to use. It is available as a daily oral pill or as a monthly extended-release injection marketed as Vivitrol. Because naltrexone requires a full detox period before initiation — typically 7 to 14 days opioid-free — it is best suited for patients who have already completed withdrawal management. Naltrexone is also FDA-approved for alcohol use disorder, where it reduces cravings and heavy drinking days.

Learn more about Naltrexone →

Buprenorphine (Suboxone)

Buprenorphine is a partial opioid agonist with a built-in ceiling effect, meaning its opioid effects plateau at moderate doses — significantly lowering the risk of respiratory depression and overdose. It is available as a sublingual film or tablet (commonly known by the brand name Suboxone, which also contains naloxone to deter misuse) and as a monthly subcutaneous injection (Sublocade). Buprenorphine can be prescribed in office-based settings by qualified providers, making it one of the most accessible MAT options. It effectively reduces cravings and withdrawal symptoms while carrying lower abuse potential than full agonists.

Learn more about Buprenorphine →

Methadone

Methadone is a full opioid agonist with more than 60 years of clinical evidence supporting its effectiveness. Administered daily at certified Opioid Treatment Programs (OTPs), methadone eliminates withdrawal symptoms, suppresses cravings, and blocks the effects of other opioids when dosed correctly. It is considered the most effective option for individuals with severe opioid use disorder, particularly those who have not responded to other medications. The structured program participation required — including regular clinic visits, counseling, and drug screening — provides an additional layer of accountability and support.

Learn more about Methadone →

Naloxone (Narcan)

Naloxone is an opioid antagonist used to rapidly reverse opioid overdoses. Available as a nasal spray (Narcan) and in injectable formulations, naloxone can restore normal breathing within minutes in a person experiencing respiratory depression from opioids. In 2023, Narcan nasal spray became available over the counter without a prescription, making it more accessible than ever. Every person who uses opioids, is prescribed high-dose opioid pain medication, or has a loved one at risk should keep naloxone on hand — it is safe, effective, and saves lives.

Learn more about Naloxone →

MAT resources and information:

Find Medication-Assisted Treatment (MAT) by State

Browse medication-assisted treatment (mat) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)