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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Medication-Assisted Treatment (MAT) Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.

Found 300 treatment centers offering medication-assisted treatment (mat) across the United States.

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Dearborn, MI

Situated in Dearborn, MI, ACC Dearborn specializes in outpatient treatment for individuals dealing with substance use issues, including both adults and children facing significant mental health challenges. The center offers tailored programs that address the needs of adolescents and adult men and women, fostering a nurturing environment to support their recovery journeys. Employing techniques like anger management, brief intervention, and cognitive behavioral therapy, ACC Dearborn emphasizes personalized care to encourage long-term sobriety. With a devoted team of experts, the center is focused on providing exceptional treatment for clients of all genders who are aiming to conquer addiction and enhance their mental health.

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Queensbury, NY

Situated in Queensbury, NY, ACCA Quaker Road stands out as a premier rehabilitation facility dedicated to substance use recovery for adult males. The center offers both long-term and 24-hour residential care, creating a nurturing atmosphere for those on the path to recovery. By employing evidence-based methods like anger management, cognitive behavioral therapy, and motivational incentives, ACCA Quaker Road personalizes its treatment plans to suit the distinct requirements of each individual. Catering to adult men, seniors, and younger adult males, the center is committed to providing exceptional care and support during the recovery process.

ACCESS Blue Island Medical Center

ACCESS Blue Island Medical Center, located in Blue Island, IL, provides outpatient treatment for adults dealing with substance use disorders, particularly those with concurrent severe mental health challenges or emotional issues in children. The facility employs various therapeutic approaches, including cognitive behavioral therapy and the Matrix Model, to deliver holistic support. Tailored programs are available for both men and women, alongside services designed for clients living with HIV or AIDS. Focusing on young adults as well, this center fosters a nurturing atmosphere conducive to recovery. By offering outpatient treatments with methadone, buprenorphine, or naltrexone, ACCESS Blue Island Medical Center emphasizes personalized care for all clients.

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Situated in Bloomingdale, IL, the ACCESS Martin T Russo Family Hlth Ctr provides expert outpatient care for individuals dealing with substance use and co-occurring mental health challenges, serving both adults and children. The facility offers various treatment options, including outpatient programs featuring methadone, buprenorphine, and naltrexone, alongside standard outpatient services. It employs proven strategies such as brief intervention, the Matrix Model, and motivational interviewing to ensure effective support. Designed to meet the specific needs of adult men, women, and individuals living with HIV or AIDS, the center caters to both adult and young adult populations of all genders. Committed to delivering high-quality, personalized care, this center stands as a symbol of hope for those in need of thorough rehabilitation options.

ACDM Assessment and Csl of Guilford

ACDM Assessment and Csl of Guilford, located in Greensboro, NC, provides outpatient services for substance use disorders through proven methods such as cognitive behavioral therapy, motivational interviewing, and dedicated counseling for addiction. This facility serves a diverse clientele, including adult males and females, seniors, and active military members. With programs specifically designed for each demographic, the center focuses on delivering personalized care that meets the distinct requirements of every individual. The highly skilled team at this center is committed to offering top-notch support for those on the path to recovery. For those seeking thorough substance use treatment in Greensboro, ACDM Assessment and Csl of Guilford presents valuable options.

ACT/Counseling and Education

Situated in Scottsdale, Arizona, the ACT/Counseling and Education center provides extensive outpatient services addressing substance use, co-occurring disorders, and significant mental health issues in adults, as well as serious emotional disturbances in children. Employing proven techniques like 12-step facilitation, brief intervention, and cognitive behavioral therapy, this center has dedicated programs specifically designed for active duty military members, and both men and women. Catering to adults and young adults of all genders, the facility ensures high-quality, personalized care that meets individual needs, establishing itself as an essential option for those pursuing effective rehabilitation solutions.

ACTS Behavioral Health and

Situated in Lynnwood, WA, ACTS Behavioral Health specializes in outpatient services for adults facing substance use challenges alongside significant mental health disorders, as well as for children experiencing serious emotional disturbances. Utilizing evidence-based methodologies such as anger management, brief intervention, and cognitive behavioral therapy, this center develops personalized programs for each individual. Catering to a diverse range of clients, including adults and children/adolescents of all genders, ACTS Behavioral Health is committed to delivering high-quality care through customized treatment plans. If you or someone you know is in need of thorough and effective addiction support, this program may be the ideal option for you.

ACTS Behavioral Health and

In Lakewood, WA, ACTS Behavioral Health provides comprehensive treatment programs for adults struggling with substance use and co-occurring mental health conditions, as well as for children with serious emotional disturbances. Their services encompass intensive outpatient, outpatient, and regular outpatient levels of care. Utilizing therapeutic approaches such as anger management, brief intervention, and cognitive behavioral therapy, ACTS Behavioral Health delivers tailored support. They offer personalized treatment plans for adults and children, accommodating both male and female clients who are looking for effective addiction recovery and mental health support in a nurturing setting.

ADAP Counseling Services
Port Saint Lucie, FL

ADAP Counseling Services located in Port Saint Lucie, FL, delivers outpatient treatment for substance use tailored to both adults and young adults. The center employs methods like cognitive-behavioral therapy, anger management, and motivational interviewing to create personalized care plans for each individual. With programs specifically designed for men and women, ADAP Counseling Services fosters a holistic and inclusive atmosphere for rehabilitation. Their commitment to high-quality care and individualized treatment options positions them as a significant asset for individuals looking for compassionate and effective support in overcoming addiction.

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ADAP Counseling Services in Stuart, FL, provides specialized outpatient addiction recovery programs for adults and adolescents. Employing evidence-based methods such as anger management, cognitive behavioral therapy, and motivational interviewing, the center delivers customized support to both male and female participants. ADAP Counseling Services prioritizes unique treatment trajectories, guaranteeing that every person gets the precise assistance required for their journey toward sobriety. The facility's dedication to superior care and bespoke recovery strategies makes it a noteworthy option for individuals pursuing impactful and thorough substance abuse treatment in the Stuart community.

ADAPT Addictions and Behavioral Health

ADAPT Addictions and Behavioral Health, located in Bismarck, ND, offers outpatient services specifically designed for adults and young adults facing substance use challenges. The facility emphasizes 12-step programs, anger management strategies, and short-term intervention techniques. It also has specialized offerings for individuals who have encountered intimate partner violence, domestic violence, trauma, and those dealing with both mental health issues and substance use problems. Committed to personalized treatment, ADAPT fosters a welcoming and supportive atmosphere for clients of all genders. For those seeking thorough and effective addiction support, this center is devoted to delivering high-quality care to aid in the recovery journey.

ADAPT Aware Zone Inc

ADAPT Aware Zone Inc, located in Whittier, CA, specializes in outpatient services for substance use treatment, particularly emphasizing Anger Management, Brief Intervention, and Contingency Management/Motivational Incentives. This center has dedicated programs for Active Duty Military members, as well as services for Adolescents and Adult Men. It offers assistance to both Adults and Children/Adolescents, ensuring that care is customized for individuals of all genders who are seeking support with addiction. With a strong dedication to high-quality treatment and evidence-based practices, ADAPT Aware Zone Inc stands out as a reliable option for those aiming to overcome substance use challenges in a compassionate outpatient environment.

ADAPT Counseling Services

ADAPT Counseling Services located in Evansville, IN, delivers an extensive range of substance abuse treatment for both adults and children facing concurrent mental health issues. The center features a variety of treatment formats, including intensive outpatient, outpatient, and standard outpatient programs that employ proven methods like 12-step facilitation, anger management, and brief intervention. ADAPT also offers specialized programs aimed at active duty military members, adolescents, and adult men, accommodating a wide spectrum of ages and genders, including both women and men. With an emphasis on personalized care and a nurturing atmosphere, the facility is dedicated to providing high-quality treatment for those in need of effective and empathetic rehabilitation support.

ADAPT MOTS only Madrone

Madrone, located in Roseburg, OR, delivers extensive treatment for substance abuse and is proficient in addressing co-occurring disorders among both adults and children. This center features adaptable outpatient options, which include intensive outpatient programs and medication-assisted treatment. Emphasizing tools such as 12-step facilitation, anger management, and short interventions, the facility customizes its approach to meet each person's specific needs. It also offers distinct programs for active military members, adult men and women, and services tailored for children and teenagers, ensuring focused care for every individual. With a strong commitment to high-quality treatment and a variety of specialized methods, Madrone is resolute in assisting individuals throughout their recovery process.

ADAPT Psychology Inc

ADAPT Psychology Inc, located in Henderson, KY, specializes in outpatient services for individuals dealing with substance use challenges and concurrent mental health conditions in adults, along with severe emotional issues in children. The center employs methods such as 12-step facilitation, anger management techniques, and brief interventions to create customized treatment plans for men, women, and seniors. With specific initiatives for active military personnel and adolescents, ADAPT Psychology Inc prioritizes person-centered care, ensuring that rehabilitation services are thorough and nurturing. Clients are welcomed into a supportive environment that promotes recovery and well-being for anyone in need of assistance.

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West Bloomfield, MI

ADF Counseling, situated in West Bloomfield, MI, is a facility dedicated to providing outpatient services for individuals struggling with substance abuse and co-occurring mental health issues. Their specialized programs cater to adults and young people, incorporating approaches like 12-step facilitation, anger management, and concise intervention strategies. The center offers personalized support to active duty military members, as well as adult men and women. They also extend their services to seniors of all genders, ensuring a compassionate and effective treatment experience. ADF Counseling is committed to delivering thorough care designed to meet the distinct requirements of each person seeking assistance for addiction or psychological well-being.

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Commerce Township, MI

ADF Counseling Associates, located in Commerce Township, MI, provides outpatient treatment for individuals, both adults and children, who are dealing with substance use problems alongside significant mental health challenges. The program incorporates techniques such as 12-step facilitation, anger management, and brief intervention. This center offers tailored services specifically designed for active military members, as well as programs aimed at adult men and women. Catering to a diverse population that includes seniors and individuals of all genders, ADF Counseling Associates is committed to delivering personalized care that addresses unique needs. Emphasizing thorough support and evidence-based methodologies, this facility stands out as a reliable option for effective rehabilitation in a supportive atmosphere.

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ADMHA SA and Recovery Services in Springfield, MA, delivers outpatient addiction treatment and targeted assistance for co-occurring mental health and substance use issues in adults, as well as emotional challenges in young people. Their regular outpatient services employ proven methods such as brief intervention, cognitive behavioral therapy, and relapse prevention strategies. Distinctive programs are available for active military members, teenagers, and adult men. ADMHA SA and Recovery Services accommodates both adult and young clients of all genders, offering personalized care. This facility stands as a key provider of thorough and impactful recovery options, prioritizing high-quality treatment and diverse specialized services.

AGS Programs LLC
Baltimore, MD

AGS Programs LLC located in Baltimore, MD, provides focused rehabilitation solutions for adult men in need of substance abuse treatment. This center offers various treatment options, which encompass long-term residential care, outpatient programs, and standard outpatient services. The therapeutic methods employed include cognitive behavioral therapy, anger management, and the Matrix Model. Additionally, AGS Programs LLC addresses the needs of distinct groups, including active duty military members, adult males, and those affected by intimate partner violence. With programming designed for adults, seniors, and young adults, the facility guarantees a thorough and individualized recovery experience for male clients.

AGS Programs LLC
Gwynn Oak, MD

AGS Programs LLC, located in Gwynn Oak, MD, delivers a variety of rehabilitation services specifically designed for men facing challenges with substance use. The center offers a spectrum of treatment options including long-term residential programs, outpatient care, and routine outpatient services, all of which utilize cognitive behavioral therapy, anger management techniques, and the Matrix Model. AGS Programs LLC is dedicated to providing specialized support for active military personnel, adult males, and those who have endured intimate partner or domestic violence. This facility serves a diverse range of individuals, from adults to seniors and young adults, fostering a nurturing environment for male clients in need of comprehensive addiction recovery and transitional housing assistance.

AGS Programs LLC
Baltimore, MD

AGS Programs LLC, located in Baltimore, MD, delivers expert recovery support for individuals grappling with addiction and concurrent mental health challenges, catering to both younger and adult demographics. Their comprehensive offerings include robust intensive outpatient programs, structured day treatment services, and partial hospitalization options. Employing evidence-based approaches such as anger management, cognitive behavioral therapy, and the Matrix Model, the center crafts individualized recovery journeys. They also feature distinct treatment pathways for active military personnel, teenagers, and adult males, guaranteeing focused interventions. AGS Programs LLC provides compassionate and customized assistance to all clients, regardless of gender or age.

Frequently Asked Questions

What is Medication-Assisted Treatment (MAT)?
MAT combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction treatment. Medications normalize brain chemistry, block euphoric effects of substances, relieve physiological cravings, and normalize body functions without negative effects of substance use. MAT is the gold standard for opioid and alcohol use disorders.
What medications are used in MAT?
For opioid use disorder: methadone, buprenorphine (Suboxone, Sublocade), and naltrexone (Vivitrol). For alcohol use disorder: naltrexone, acamprosate, and disulfiram. Each medication has unique benefits and considerations. A physician experienced in addiction medicine determines the most appropriate option based on individual circumstances, substance used, and treatment goals.
Is MAT just replacing one addiction with another?
No, this is a common misconception. MAT medications are prescribed at stable, therapeutic doses and don't produce euphoria when taken as directed. They're medicine, not substitution. MAT allows normal functioning, eliminates cravings, prevents withdrawal, dramatically reduces overdose risk, and enables engagement in therapy and rebuilding life. Research consistently shows MAT saves lives and improves outcomes.
How long does MAT last?
MAT duration varies by individual needs. Some people benefit from months of treatment, others years or indefinitely. There's no predetermined timeline. Research shows longer MAT duration improves outcomes and reduces overdose risk. Decisions about duration should be made collaboratively with healthcare providers based on stability, quality of life, and recovery goals, not arbitrary timelines.
Does insurance cover MAT?
Most health insurance plans cover MAT under mental health and substance use benefits. The Affordable Care Act and Mental Health Parity Act require coverage for addiction treatment including MAT. Coverage includes medications, office visits, counseling, and therapy. Contact your insurance provider or treatment center admissions to verify specific coverage and costs.

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.

MAT Medications for Opioid Use Disorder

Three FDA-approved medications treat opioid addiction:

  • Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
  • Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
  • Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.

MAT for Alcohol Use Disorder

FDA-approved medications for alcohol addiction:

  • Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
  • Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
  • Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking

Comprehensive Treatment Approach

MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.

Addressing Stigma and Misconceptions

MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.

Finding MAT Treatment

Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.

Harm Reduction and Medication-Assisted Treatment

Harm reduction is a public health philosophy that meets people where they are in their relationship with substance use. Rather than demanding abstinence as a precondition for support, harm reduction focuses on reducing the negative health, social, and economic consequences of drug use while keeping individuals alive, safe, and connected to care. This pragmatic approach recognizes that not everyone is ready or able to stop using substances immediately, and that incremental steps toward health are meaningful and worth supporting.

Harm reduction programs take many forms in communities across the country. Needle exchange and syringe service programs reduce the spread of HIV and hepatitis C among people who inject drugs. Naloxone (Narcan) distribution puts lifesaving overdose reversal medication directly into the hands of people who use drugs and their loved ones. Drug checking services, including fentanyl test strips, help people identify dangerous adulterants in their supply. Supervised consumption sites, operating in several countries and piloted in the United States, provide sterile environments with medical staff on hand to prevent fatal overdoses. Low-threshold MAT programs remove barriers to treatment by offering same-day starts, flexible scheduling, and minimal requirements for enrollment.

Harm reduction and abstinence are not competing philosophies — they are complementary approaches along a continuum of care. Many people who initially engage with harm reduction services eventually choose to pursue abstinence-based recovery. Research consistently shows that harm reduction programs serve as a critical bridge, connecting individuals to treatment they might never have accessed otherwise. Forcing a choice between the two creates a false dichotomy that costs lives.

MAT is itself a cornerstone harm reduction strategy. Buprenorphine and methadone maintenance programs dramatically reduce overdose deaths — studies show a 50% or greater reduction in all-cause mortality among patients receiving opioid agonist therapy. Beyond preventing fatal overdoses, MAT reduces HIV and hepatitis C transmission by decreasing injection drug use, lowers criminal activity and incarceration rates, and improves overall quality of life, housing stability, and employment outcomes. These benefits occur even when patients are not fully abstinent from all substances. By stabilizing brain chemistry and eliminating the desperate cycle of withdrawal and compulsive use, MAT gives people the stability they need to rebuild their lives. Facilities offering MAT as part of a harm reduction framework can be found through our opioid rehab directory.

FDA-Approved Medications: Detailed Guides

The U.S. Food and Drug Administration has approved several medications for the treatment of opioid and alcohol use disorders. Each works through a different mechanism and is suited to different clinical situations. Understanding the distinctions can help patients and families make informed decisions alongside their treatment providers. Explore our in-depth guides below.

Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist that completely blocks the euphoric and sedative effects of opioids, removing the incentive to use. It is available as a daily oral pill or as a monthly extended-release injection marketed as Vivitrol. Because naltrexone requires a full detox period before initiation — typically 7 to 14 days opioid-free — it is best suited for patients who have already completed withdrawal management. Naltrexone is also FDA-approved for alcohol use disorder, where it reduces cravings and heavy drinking days.

Learn more about Naltrexone →

Buprenorphine (Suboxone)

Buprenorphine is a partial opioid agonist with a built-in ceiling effect, meaning its opioid effects plateau at moderate doses — significantly lowering the risk of respiratory depression and overdose. It is available as a sublingual film or tablet (commonly known by the brand name Suboxone, which also contains naloxone to deter misuse) and as a monthly subcutaneous injection (Sublocade). Buprenorphine can be prescribed in office-based settings by qualified providers, making it one of the most accessible MAT options. It effectively reduces cravings and withdrawal symptoms while carrying lower abuse potential than full agonists.

Learn more about Buprenorphine →

Methadone

Methadone is a full opioid agonist with more than 60 years of clinical evidence supporting its effectiveness. Administered daily at certified Opioid Treatment Programs (OTPs), methadone eliminates withdrawal symptoms, suppresses cravings, and blocks the effects of other opioids when dosed correctly. It is considered the most effective option for individuals with severe opioid use disorder, particularly those who have not responded to other medications. The structured program participation required — including regular clinic visits, counseling, and drug screening — provides an additional layer of accountability and support.

Learn more about Methadone →

Naloxone (Narcan)

Naloxone is an opioid antagonist used to rapidly reverse opioid overdoses. Available as a nasal spray (Narcan) and in injectable formulations, naloxone can restore normal breathing within minutes in a person experiencing respiratory depression from opioids. In 2023, Narcan nasal spray became available over the counter without a prescription, making it more accessible than ever. Every person who uses opioids, is prescribed high-dose opioid pain medication, or has a loved one at risk should keep naloxone on hand — it is safe, effective, and saves lives.

Learn more about Naloxone →

MAT resources and information:

Find Medication-Assisted Treatment (MAT) by State

Browse medication-assisted treatment (mat) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)