Medication-Assisted Treatment (MAT) Centers
Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.
Found 300 treatment centers offering medication-assisted treatment (mat) across the United States.
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AGS Programs LLC in Baltimore, MD delivers tailored addiction recovery support exclusively for women. Their offerings include extended residential stays, day treatment, and standard outpatient services. Employing approaches such as anger management, cognitive behavioral therapy, and the Matrix Model, the center ensures thorough recovery assistance. Specialized care is available for active military members, adult women, and survivors of domestic abuse. Catering to adults, seniors, and young adults, AGS Programs LLC focuses on the distinct requirements of female individuals. Clients can anticipate high-quality treatment and successful rehabilitation methodologies at this establishment.
AIDS Action Coalition in Huntsville, AL, provides targeted rehabilitation for individuals facing substance use challenges and accompanying mental health issues, serving both adults and younger individuals. Their treatment options include intensive outpatient, outpatient, and standard outpatient programs, incorporating methods like 12-step facilitation, anger management, and brief interventions. Special care is extended to those with a history of trauma, individuals living with HIV/AIDS, and those dealing with the complexities of dual diagnoses. This center is dedicated to offering personalized, high-quality support for recovery to adults and young adults of all gender identities, cultivating a nurturing space for progress.
AIM Advaita Integrated Medicine in Raleigh, NC, is dedicated to providing thorough substance abuse care and targeted support for those facing concurrent mental health challenges. They offer intensive outpatient, outpatient services, and medication-assisted treatment including methadone, buprenorphine, or naltrexone. Employing proven methods such as anger management, CBT, and brief interventions, the center serves adult men, adult women, and individuals with co-occurring disorders. Serving adults and adolescents, AIM Advaita Integrated Medicine delivers individualized attention to all clients, prioritizing effective and customized treatment strategies.
AIM Target Programs Inc, situated in Fort Myers, Florida, provides outpatient services for adults and young adults dealing with substance use issues. Their unique programs are designed specifically for those who have experienced intimate partner violence and domestic abuse. Emphasizing methods such as 12-step support, anger management, and brief intervention strategies, the center offers personalized care to meet the distinctive requirements of each client. Catering to both men and women, AIM Target Programs Inc ensures high-quality, evidence-informed treatment within a nurturing atmosphere. If you or someone you care about is looking for compassionate and effective addiction support, this center is committed to guiding individuals toward recovery.
AISOL LLC, situated in West Palm Beach, FL, delivers complete addiction recovery solutions, encompassing both detox and comprehensive substance use treatment. The center features distinct programs designed for adult males, adult females, and individuals managing HIV or AIDS, guaranteeing personalized attention for a broad spectrum of client needs. Their treatment modalities span from hospital-based inpatient detoxification to residential detoxification, ensuring a seamless progression of care. Employing scientifically validated methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, AISOL LLC is dedicated to fostering complete well-being. Catering to adult and young adult individuals of all gender identities, AISOL LLC is committed to delivering high-caliber treatment and bespoke encouragement for sustained sobriety.
AK Add Rehabilitation Services Inc, situated in Wasilla, AK, provides a full spectrum of care for those battling addiction. Their offerings include intensive outpatient, long-term residential, and standard outpatient services. Treatment modalities employed by the center encompass 12-step facilitation, anger management techniques, and brief intervention strategies. They also offer specialized support for adult men, adult women, and individuals affected by intimate partner or domestic violence. Dedicated to addressing dual diagnoses of substance use and mental health conditions, this facility supports adults and young adults of all genders with tailored treatment and assistance.
Located in Baltimore, MD, AKT Healthcare Inc provides extensive rehabilitation services designed for adults and seniors facing challenges with substance abuse and co-existing mental health issues. This center specializes in long-term residential care, which encompasses detox services and round-the-clock assistance, employing evidence-based methods like 12-step programs and anger management techniques. Tailored programs are available for youth, individuals impacted by intimate partner violence, domestic violence, and sexual abuse. AKT Healthcare Inc emphasizes personalized treatment plans, ensuring that both male and female clients receive dedicated care. Discover empathetic and impactful rehabilitation at this esteemed facility.
ALEF Behavioral Group, located in Reidsville, NC, delivers tailored outpatient addiction recovery services for adults and young adults. Their offerings include intensive outpatient care, standard outpatient services, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center employs strategies such as 12-step facilitation, anger management, and brief intervention, all customized to meet individual client requirements. ALEF Behavioral Group extends specialized care to pregnant and postpartum women, and maintains distinct programs for male and female clients to foster a supportive, gender-sensitive recovery atmosphere. Opt for ALEF Behavioral Group for reliable and impactful substance use disorder treatment.
ALEF Behavioral Group Reidsville, located in Reidsville, NC, specializes in providing tailored treatment for substance use disorders for both adults and young adults. The facility features intensive outpatient programs, standard outpatient services, and options for methadone/buprenorphine or naltrexone treatment. Emphasizing 12-step support, anger management, and brief intervention techniques, the center serves clients of all genders. Additionally, it offers specialized programs for pregnant and postpartum women, ensuring holistic support for every individual. Committed to high-quality care and personalized treatment plans, this center is an essential resource for effective addiction recovery in the Reidsville region.
ALPHA Behavioral Health Center, located in Camden, SC, provides targeted treatment for substance use via both outpatient and traditional outpatient services. Their comprehensive approach encompasses anger management, brief interventions, and cognitive-behavioral therapy. The center offers customized programs designed for adolescents, adult men, and adult women, addressing the needs of both adults and younger clients. Emphasizing personalized care, ALPHA Behavioral Health Center is open to all clients, regardless of gender, who are in pursuit of effective rehabilitation solutions. The center is committed to offering top-notch treatment options through a variety of specialized programs aimed at accommodating the unique requirements of each individual.
ALPHA Behavioral Health Center in Chesterfield, SC, delivers outpatient support for individuals grappling with substance use issues, serving both young people and adults. The center employs proven therapeutic methods like anger control strategies, concise intervention techniques, and cognitive behavioral therapy within its regular outpatient services. They offer distinct programs designed for adult men, adult women, and adolescents, ensuring that a wide range of people receive relevant care. Anyone needing effective substance use treatment in a nurturing setting may find ALPHA Behavioral Health Center to be a valuable partner in their path to recovery.
Nestled in Las Cruces, NM, ALT Recovery Group is a dedicated facility providing extensive outpatient care for adults and children facing challenges with detoxification, substance use disorders, and co-occurring mental health concerns. They offer a range of outpatient detoxification options, alongside medication-assisted treatment using methadone, buprenorphine, or naltrexone, all delivered with a strong emphasis on tailored support. Employing therapeutic modalities like anger management, brief intervention, and cognitive behavioral therapy, the center serves a diverse population of adults and young adults. ALT Recovery Group distinguishes itself through its dedication to crafting unique treatment strategies, guaranteeing superior assistance for everyone pursuing recovery from addiction and mental health issues.
Situated in Chatsworth, CA, ALT Recovery Group 2 delivers an extensive selection of outpatient programs focused on detoxification and substance abuse rehabilitation. Emphasizing 12-step guidance, anger management sessions, and short-term intervention strategies, this center serves adult men and women, including those who have faced domestic or intimate partner violence. ALT Recovery Group 2 is dedicated to assisting both adults and young adults of all gender identities, offering outpatient detox services alongside treatments with methadone, buprenorphine, or naltrexone. The center's commitment to high-quality care and tailored programs positions it as an essential support for individuals in need of effective addiction recovery solutions.
ALTR of Jackson LLC, located in Jackson, MS, provides outpatient treatment services for both adults and young adults dealing with substance use issues. The center features tailored programs designed for men and women, as well as those who have faced traumatic experiences. The methodologies employed comprise 12-step facilitation, brief intervention strategies, and cognitive behavioral therapy (CBT). Prioritizing high-quality care, ALTR of Jackson LLC also offers outpatient services that include methadone, buprenorphine, or naltrexone treatments. The facility serves both male and female patients, delivering a thorough and customized approach to recovery in a nurturing setting for individuals in need of assistance.
AM/PM Culver City Budget DUI School, located in Culver City, CA, delivers a full spectrum of care for individuals battling substance use disorders. Their offerings include intensive outpatient, standard outpatient, and flexible outpatient services. The center is equipped to support active military members, adult males, and adult females, with a particular emphasis on providing gender-inclusive care for adults and young adults. AM/PM Culver City Budget DUI School is dedicated to a holistic treatment philosophy, aiming to provide effective and supportive services for recovery.
AM/PM VanNuys Driver Safety DUI School, located in Van Nuys, CA, provides extensive substance abuse treatment through a variety of programs, including intensive outpatient and standard outpatient options. This center is committed to serving active military members as well as adult men and women. Catering to adults and young adults of all genders, it adopts a customized strategy for recovery. With an emphasis on high-quality care, the offerings at AM/PM VanNuys Driver Safety DUI School prioritize a well-rounded treatment approach. Clients will receive individualized assistance designed to meet their specific requirements, fostering a nurturing atmosphere for successful rehabilitation.
AM/PM West LA Convenient Driver Safety, located in Los Angeles, CA, provides a thorough range of substance use recovery services, including intensive outpatient, outpatient, and regular outpatient programs. The center serves active duty military members, adult men and women, as well as young adults. Committed to delivering high-quality care, it offers various services designed to meet the unique needs of each individual. The center takes a holistic approach, focusing on the underlying issues that contribute to addiction. With specialized programs tailored to different demographics, this facility guarantees that every client benefits from customized and impactful treatment.
Situated in Los Angeles, CA, the AMAAD Institute delivers a wide array of services aimed at treating substance use disorders. This center operates both outpatient and regular outpatient treatment programs that incorporate evidence-based methods, including 12-step facilitation, brief interventions, and cognitive behavioral therapy. The AMAAD Institute is dedicated to assisting active duty military members as well as adult men and women, addressing the needs of both young adults and older individuals. Emphasizing personalized care and support, this facility offers transitional housing, halfway houses, and sober living arrangements. With a strong dedication to high-quality care, the AMAAD Institute fosters a secure and encouraging atmosphere for those pursuing recovery from addiction.
At AMPT Up for Change LLC in Houston, TX, embark on a journey towards meaningful transformation. This center specializes in treatment for substance use and co-occurring disorders for both adults and children. It offers a variety of programs including intensive outpatient, outpatient, and standard outpatient options, focusing on personalized strategies like anger management, cognitive behavioral therapy, and motivational interviewing. With dedicated programs for men, women, and individuals facing concurrent mental health challenges, the center ensures holistic care for all clients. Catering to both genders and different age groups, AMPT provides customized support to foster recovery and wellbeing. Experience empathetic and effective rehabilitation at this center, which emphasizes sustained health and recovery.
AMS of Delaware LLC, located in Rehoboth Beach, DE, delivers thorough addiction recovery services for adults and young adults. Their expertise lies in detoxification and substance abuse treatment, offering intensive outpatient and standard outpatient options, including outpatient detox. Employing techniques like anger management, brief intervention, and cognitive behavioral therapy, the center customizes care plans to suit each person's unique journey. AMS of Delaware LLC also provides dedicated programs for adult men, adult women, and individuals facing co-occurring mental health and substance use challenges. Prioritizing excellent care, this establishment fosters a nurturing setting for those pursuing freedom from addiction.
AMS of Wisconsin LLC, located in Onalaska, WI, provides a wide array of treatments aimed at detoxification, substance abuse recovery, and addressing co-occurring mental health issues for both adults and children. Their programs include intensive outpatient and outpatient services that utilize evidence-based methods such as cognitive behavioral therapy, anger management, and brief interventions. This center supports men and women, including those who have faced domestic violence or intimate partner abuse. With dedicated offerings for adults and seniors of all genders, AMS of Wisconsin LLC is committed to delivering personalized care, making it an essential facility for individuals seeking effective rehabilitation options in the Onalaska region.
Frequently Asked Questions
What is Medication-Assisted Treatment (MAT)?
What medications are used in MAT?
Is MAT just replacing one addiction with another?
How long does MAT last?
Does insurance cover MAT?
About Medication-Assisted Treatment (MAT)
Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.
MAT Medications for Opioid Use Disorder
Three FDA-approved medications treat opioid addiction:
- Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
- Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
- Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.
MAT for Alcohol Use Disorder
FDA-approved medications for alcohol addiction:
- Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
- Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
- Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking
Comprehensive Treatment Approach
MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.
Addressing Stigma and Misconceptions
MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.
Finding MAT Treatment
Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.
Harm Reduction and Medication-Assisted Treatment
Harm reduction is a public health philosophy that meets people where they are in their relationship with substance use. Rather than demanding abstinence as a precondition for support, harm reduction focuses on reducing the negative health, social, and economic consequences of drug use while keeping individuals alive, safe, and connected to care. This pragmatic approach recognizes that not everyone is ready or able to stop using substances immediately, and that incremental steps toward health are meaningful and worth supporting.
Harm reduction programs take many forms in communities across the country. Needle exchange and syringe service programs reduce the spread of HIV and hepatitis C among people who inject drugs. Naloxone (Narcan) distribution puts lifesaving overdose reversal medication directly into the hands of people who use drugs and their loved ones. Drug checking services, including fentanyl test strips, help people identify dangerous adulterants in their supply. Supervised consumption sites, operating in several countries and piloted in the United States, provide sterile environments with medical staff on hand to prevent fatal overdoses. Low-threshold MAT programs remove barriers to treatment by offering same-day starts, flexible scheduling, and minimal requirements for enrollment.
Harm reduction and abstinence are not competing philosophies — they are complementary approaches along a continuum of care. Many people who initially engage with harm reduction services eventually choose to pursue abstinence-based recovery. Research consistently shows that harm reduction programs serve as a critical bridge, connecting individuals to treatment they might never have accessed otherwise. Forcing a choice between the two creates a false dichotomy that costs lives.
MAT is itself a cornerstone harm reduction strategy. Buprenorphine and methadone maintenance programs dramatically reduce overdose deaths — studies show a 50% or greater reduction in all-cause mortality among patients receiving opioid agonist therapy. Beyond preventing fatal overdoses, MAT reduces HIV and hepatitis C transmission by decreasing injection drug use, lowers criminal activity and incarceration rates, and improves overall quality of life, housing stability, and employment outcomes. These benefits occur even when patients are not fully abstinent from all substances. By stabilizing brain chemistry and eliminating the desperate cycle of withdrawal and compulsive use, MAT gives people the stability they need to rebuild their lives. Facilities offering MAT as part of a harm reduction framework can be found through our opioid rehab directory.
FDA-Approved Medications: Detailed Guides
The U.S. Food and Drug Administration has approved several medications for the treatment of opioid and alcohol use disorders. Each works through a different mechanism and is suited to different clinical situations. Understanding the distinctions can help patients and families make informed decisions alongside their treatment providers. Explore our in-depth guides below.
Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist that completely blocks the euphoric and sedative effects of opioids, removing the incentive to use. It is available as a daily oral pill or as a monthly extended-release injection marketed as Vivitrol. Because naltrexone requires a full detox period before initiation — typically 7 to 14 days opioid-free — it is best suited for patients who have already completed withdrawal management. Naltrexone is also FDA-approved for alcohol use disorder, where it reduces cravings and heavy drinking days.
Learn more about Naltrexone →Buprenorphine (Suboxone)
Buprenorphine is a partial opioid agonist with a built-in ceiling effect, meaning its opioid effects plateau at moderate doses — significantly lowering the risk of respiratory depression and overdose. It is available as a sublingual film or tablet (commonly known by the brand name Suboxone, which also contains naloxone to deter misuse) and as a monthly subcutaneous injection (Sublocade). Buprenorphine can be prescribed in office-based settings by qualified providers, making it one of the most accessible MAT options. It effectively reduces cravings and withdrawal symptoms while carrying lower abuse potential than full agonists.
Learn more about Buprenorphine →Methadone
Methadone is a full opioid agonist with more than 60 years of clinical evidence supporting its effectiveness. Administered daily at certified Opioid Treatment Programs (OTPs), methadone eliminates withdrawal symptoms, suppresses cravings, and blocks the effects of other opioids when dosed correctly. It is considered the most effective option for individuals with severe opioid use disorder, particularly those who have not responded to other medications. The structured program participation required — including regular clinic visits, counseling, and drug screening — provides an additional layer of accountability and support.
Learn more about Methadone →Naloxone (Narcan)
Naloxone is an opioid antagonist used to rapidly reverse opioid overdoses. Available as a nasal spray (Narcan) and in injectable formulations, naloxone can restore normal breathing within minutes in a person experiencing respiratory depression from opioids. In 2023, Narcan nasal spray became available over the counter without a prescription, making it more accessible than ever. Every person who uses opioids, is prescribed high-dose opioid pain medication, or has a loved one at risk should keep naloxone on hand — it is safe, effective, and saves lives.
Learn more about Naloxone →MAT resources and information:
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