71 articles found
CDC provisional data put U.S. overdose deaths at nearly 68,000 for the year ending March 2026, about 9,500 fewer than a year earlier, while 430 counties recorded increases.
Baltimore health officials issued an advisory after benzodiazepines turned up in 31 Maryland drug samples from April to July, more than double last year's 14.
Oklahoma's HB 2941, effective Nov. 1, requires first responders to notify law enforcement of suspected overdoses and presumes fentanyl in fatal cases.
An InvestigateWest review of 134 Idaho fentanyl trafficking cases found at least 30 defendants charged without evidence of selling, facing mandatory minimums.
A Berks County jury found Jesus Martinez-Espinal guilty on nine counts of drug delivery resulting in death after a single-day overdose cluster in Reading in 2022.
The FDA accepted Orexo's resubmitted application for IZIPRY, a high-dose naloxone nasal powder, and set a March 29, 2027 target date for a decision.
An ASPE reanalysis cuts the record 2025 death-rate decline from 4.6% to about 2% once Census vintages match, leaving drug overdoses behind 22% of the real drop.
Minnesota opioid overdose deaths fell to 671 in 2025, a third consecutive decline, while total drug deaths rose 3% to 1,025 as stimulant deaths increased.
A new pharmacokinetic model traces how intranasal naloxone reaches brain opioid receptors fast enough to restore breathing, and why fentanyl dose changes the race.
Volunteers across western North Carolina hand out naloxone, test drugs and deliver supplies, as rural counties absorb 42% of the state's overdoses.
Pennsylvania's Supreme Court upheld two drug delivery resulting in death convictions, declining to shield people who pooled drugs with the person who died.
CDC provisional data show about 3,650 New York overdose deaths in the 12 months ending May 2026, roughly 8% fewer than a year earlier and far below the state's two-year drop.
DeSantis credits the S.A.F.E. grant program as the 2025 medical examiners report shows fentanyl-caused deaths falling from about 5,000 to roughly 2,000.
A University of New Mexico review finds methamphetamine and fentanyl used together may sharpen reward and relapse, with mu-opioid receptors mediating the effect.
At a Wilkes-Barre roundtable with Sen. Dave McCormick, the attorney general attributed declining overdose deaths to interagency coordination and prevention.
Los Angeles County confirmed its first cychlorphine death, a February fatality identified this month, in a warning that fentanyl test strips miss the drug.
Two years after Gov. Spencer Cox created Utah's Fentanyl Task Force, the DEA says agents have seized nearly one million fentanyl pills in the state this year.
Security officers across Southern Nevada's transit system began carrying Narcan on July 1 and have used it in 19 overdose responses in the first 90 days.
Bernalillo County proposed an emergency declaration to fund street medicine, overdose tracking and jail reentry care where six people a week die of opioids.
Dane County installed two free harm reduction vending machines stocked with naloxone in Sun Prairie and Stoughton, extending a program that had operated only in Madison.
Robeson County's sheriff issued a public safety alert after four suspected overdose deaths in one week, warning that a more potent batch of fentanyl and cocaine is circulating.
Hamilton County, Tennessee recorded 89 overdose deaths through September with fentanyl in six of ten, as recovery advocates took naloxone outreach to Chattanooga.
A NIST analysis of 4,563 drug samples finds fentanyl adulterants now average six or more per sample, with sharp regional differences.
Louisiana health officials confirmed cychlorphine in at least two overdose deaths since December 2025 and warned the potent opioid may require repeated naloxone doses.
The Postal Service issued a $1 semipostal stamp honoring fentanyl awareness, with net proceeds going to the National Institute on Drug Abuse.
An FDA final order exempts certain clinical toxicology test systems from premarket review, clearing a barrier to oral fluid drug testing in federal programs.
Federal and local agencies launch an overdose task force in San Antonio, where police respond to about 150 overdose calls a month, and announce the first charges.
Clear Scientific's CS-1103, a first-in-class sequestrant, accelerated fentanyl clearance into urine 25-fold in a 16-person Phase 2 trial. Phase 3 is set for 2027.
Proposition 132 would make possessing any amount of fentanyl a felony with mandatory prison time and sharply raise penalties for selling it, at a cost of millions.
St. Louis County's health department reported about 200 suspected nonfatal overdoses since late August, with a cluster in the 63136 ZIP code around Jennings.
A JAMA Internal Medicine study of two Philadelphia hospitals finds severe withdrawal needing an ICU sedative rose from under 6% to about 32% as medetomidine spread.
Corrections data compiled by the Correctional Association of New York show prison staff used Narcan 51% more often in 2025, with 12 deaths in each of the past two years.
Austin-Travis County EMS reports some overdose victims now need up to six naloxone doses, up from the typical one to two, as the fentanyl-adulterated drug supply grows more unpredictable.
Autopsy identifies 16-year-old Dante Lacourte as the victim of San Francisco's first fatal cychlorphine overdose; police arrest four and seize 20,000 pills.
Luzerne County officials warn that 12 overdose deaths in three months involved cocaine mixed with fentanyl, even as the county's overall overdose toll falls.
Pennsylvania's high court is weighing a joint-use defense to drug delivery resulting in death charges, filed more than 680 times statewide from 2021 to 2025.
Singing River Health System's free naloxone vending machines at three Mississippi Gulf Coast hospitals have distributed more than 7,800 boxes as overdose deaths fall statewide.
Mississippi reports 449 overdose deaths in 2025, a 39.8% decline from the 2021 peak of 746, as state officials prepare for International Overdose Awareness Day events.
CDC provisional data show fentanyl-related deaths dropped 54% from their peak, with total overdose fatalities falling to approximately 70,000 in 2025—a third consecutive year of decline.
SAMHSA's April 2026 guidance restricts federal grant funds for syringe services programs, removing support for fentanyl test strips and overdose hotlines while preserving naloxone funding.
Adults 65 and older are now among the fastest-growing groups for fentanyl overdose deaths, with fatalities involving fentanyl-stimulant combinations rising over 9,000% in eight years.
Wisconsin records steepest-ever single-year drop in fentanyl overdose deaths, falling from 1,422 in 2023 to 818 in 2024, as naloxone destigmatization and treatment access expand.
The iNal patch uses microneedle technology to detect dangerous fentanyl levels and automatically release naloxone, potentially saving lives when no bystander is present.
DOJ's inspector general opens a nationwide review of DEA wiretap investigations in which agents let fentanyl shipments reach the streets.
President Trump proclaims August 2026 as National Substance Use Primary Prevention Month, emphasizing evidence-based prevention strategies and the HALT Fentanyl Act.
Colorado recorded 1,554 unintentional overdose deaths in 2025, up from 1,409 in 2024, even as the U.S. death rate hit an all-time low, state data shows.
Ohio Narcotics Intelligence Center issues urgent public safety bulletins about orphine analogs and veterinary sedatives medetomidine and xylazine appearing in the state's illicit drug supply.
Detroit's Wayne County reports 42% decline in overdose deaths for 2024, but health officials warn that carfentanil—100 times stronger than fentanyl—threatens to reverse progress.
Arizona's drug overdose mortality now doubles the national average amid a 17% year-over-year increase, even as U.S. deaths fall for the third consecutive year
Cuyahoga County, Ohio reports dramatic 70% decline in fentanyl overdose deaths from 2023 to 2025, with cocaine now becoming the leading drug in fatalities.
New Mexico reports 900 overdose deaths in 2025, a 21% increase while national fatalities drop 14%. Fentanyl drives crisis in Rio Arriba, Santa Fe, and Taos counties with 65%+ spikes.
Veterinary sedative medetomidine, 100-200 times more potent than xylazine, is appearing in Minnesota's illicit fentanyl supply, creating naloxone-resistant overdoses and severe withdrawal symptoms.
Scienture Holdings begins shipping REZENOPY, a 10mg naloxone nasal spray—the highest FDA-approved dose—bringing a new overdose reversal option as fentanyl deaths decline nationwide.
Study in Drug and Alcohol Dependence finds standard methadone and buprenorphine doses often inadequate for heavy fentanyl dependence, raising treatment retention concerns.
South Carolina reports 1,481 drug overdose deaths in 2024, a 31.3% decrease from 2023, with fentanyl remaining the primary contributor to fatalities.
JAMA study finds most 8th-graders and one-third of high schoolers underestimate fentanyl's lethal risk, highlighting dangerous knowledge gaps as drug overdoses rank third in youth deaths.
Georgia Senate Bill 6 legalizes possession of fentanyl testing strips starting July 1, 2026, removing a key barrier to overdose prevention in a state hit hard by the opioid crisis.
Hawaii's pioneering syringe exchange program sees dramatic decline in needle swaps as fentanyl users increasingly prefer smoking over injection, prompting statewide harm reduction policy shift through Act 106.
UNODC World Drug Report 2026 reveals 1 in 16 people worldwide now use drugs, with synthetic opioids like fentanyl, nitazenes, and orphines replacing heroin and creating unprecedented public health risks.
Attorney General Raúl Torrez launches criminal probe into claims that DEA agents allowed hundreds of thousands of fentanyl pills to reach Albuquerque streets as state leads nation in overdose death increases.
Los Angeles County reports 6% decline in drug overdose deaths for 2025, marking three years of progress as fentanyl fatalities drop 10% and harm reduction programs show results.
New research reveals the staggering tolerance levels of people who use illicit fentanyl, explaining why medication-assisted treatment protocols designed for heroin era often fail.
Trump administration policy change eliminates SAMHSA funding for fentanyl test strips, forcing Ohio health departments to rely on dwindling state and local resources as overdose deaths decline nationally.
Real-world data shows patients with fentanyl use disorder treated with monthly injectable buprenorphine stayed in treatment longer than those on daily sublingual formulations
Bipartisan legislation would establish dedicated federal funding stream for multi-jurisdictional drug task forces, with 40% of resources directed to tribal and local law enforcement
US authorities issue urgent warning to international visitors ahead of 2026 FIFA World Cup about fentanyl contamination in street drugs, as DEA reports 29% of seized pills contain lethal doses.
Trump administration ends federal support for fentanyl, xylazine, and medetomidine test strips through SAMHSA grants, reversing Biden-era harm reduction policies amid declining overdose deaths.
While overdose deaths fell 18% nationally, Colorado saw a 10% increase in fentanyl-related fatalities, with Denver reporting a 25% spike. DEA data reveals the state's unique challenges.
Health officials confirm first fatal overdose involving N-Propionitrile chlorphine, a potent synthetic opioid undetectable by standard fentanyl test strips.
Federal health officials warn about medetomidine, a veterinary tranquilizer increasingly mixed with illicit fentanyl, causing complex withdrawal syndromes and complicating overdose responses
NPR analysis reveals sustained decline in overdose mortality since August 2023 peak, marking longest decrease in four decades despite emergence of more potent street drugs