
Colorado Adds $3.5 Million to Statewide Naloxone Buying Fund
Attorney General Phil Weiser committed another $3.5 million in opioid settlement money to Colorado's naloxone bulk purchase fund, bringing the total to $6.5 million.
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Attorney General Phil Weiser committed another $3.5 million in opioid settlement money to Colorado's naloxone bulk purchase fund, bringing the total to $6.5 million.

San Francisco confirmed its first fatal overdose involving MGM-15, a kratom-derived opioid that animal tests suggest may be up to 50 times stronger than morphine.

A JAMA research letter analyzing 2.5 million nonfatal overdoses at 5,324 EMS agencies finds naloxone was given at nearly the same rate per overdose after deaths began falling in 2023.
CN Guidance & Counseling Services won a $3.75 million federal grant to send mobile treatment, peer outreach and naloxone into Nassau and Suffolk counties.
Fall River councilors questioned the glass pipes and 20 syringes in harm reduction bags from Seven Hills Behavioral Health and asked whether recipients are screened.
Los Angeles County confirmed its first cychlorphine death, a February fatality identified this month, in a warning that fentanyl test strips miss the drug.

Los Angeles County health officials say the medical examiner identified cychlorphine, a synthetic opioid more potent than fentanyl, in the county's first fatal overdose.

Security officers across Southern Nevada's transit system began carrying Narcan on July 1 and have used it in 19 overdose responses in the first 90 days.
Dane County installed two free harm reduction vending machines stocked with naloxone in Sun Prairie and Stoughton, extending a program that had operated only in Madison.
An R Street analysis of CDC and EMS data finds non-fatal opioid overdoses declining more slowly than deaths, pointing to survivability gains and a missed treatment handoff.

Robeson County's sheriff issued a public safety alert after four suspected overdose deaths in one week, warning that a more potent batch of fentanyl and cocaine is circulating.

Hamilton County, Tennessee recorded 89 overdose deaths through September with fentanyl in six of ten, as recovery advocates took naloxone outreach to Chattanooga.

El Paso County joins nine Colorado counties piloting an overdose fatality review board with CDC funding, as local deaths rose 16% and the state bucked a national decline.

A free vending machine dispensing naloxone, pregnancy tests and hygiene supplies at Copper Mountain College was restocked twice in its first week.
Houston's FRONTLINES program will use $3 million in federal money to train first responders across Harris and Fort Bend counties to reverse opioid overdoses with naloxone.
OneOhio Recovery Foundation's second regional grant cycle awarded $960,158 to four Stark County agencies for harm reduction, youth prevention and recovery services.
Michigan's Ingham County health department reported a rise in non-fatal overdoses from Oct. 2 to 4, including one suspected death, and sent teams out with naloxone.

A foundation started by a father who lost his son to an overdose delivered 500 naloxone kits to Milwaukee Public Schools, enough for every campus.

Louisiana health officials confirmed cychlorphine in at least two overdose deaths since December 2025 and warned the potent opioid may require repeated naloxone doses.

Overdose deaths among Black San Diegans fell from 159 in 2023 to 85 in 2025, the district attorney said, while methamphetamine deaths kept rising.
Utah health officials issued an urgent warning after four deaths were linked to illegal kratom-derived compounds found in supplements labeled 'cat's claw.'
A New York labor law takes effect Dec. 13, requiring most private employers to keep an opioid antagonist on hand; proposed rules leave dose counts to employers.

Minnesota's health department launched MN-OD-ALERTS, which uses near-real-time ambulance and hospital data to flag opioid overdose spikes and warn local agencies.

Gov. Matt Meyer signed Senate Bill 249 and Executive Order 28, creating a licensing framework for harm-reduction programs and decriminalizing paraphernalia.
St. Louis County's health department reported about 200 suspected nonfatal overdoses since late August, with a cluster in the 63136 ZIP code around Jennings.

Dr. Stephen Loyd, the eighth director of West Virginia's Office of Drug Control Policy, resigned this month after being moved under a cabinet secretary.

Orexo completed a resubmission of its new drug application for IZIPRY, a high-dose naloxone nasal powder, answering a 2024 FDA rejection letter.
Austin-Travis County EMS reports some overdose victims now need up to six naloxone doses, up from the typical one to two, as the fentanyl-adulterated drug supply grows more unpredictable.

OSHA released a September 24, 2026, fact sheet advising employers on stocking naloxone and training workers to reverse opioid overdoses, though it stops short of mandatory requirements.

Volunteers handed out free naloxone at more than 1,000 sites in all 50 states on Sept. 24 for Save a Life Day, as federal funding rules kept drug test strips off many tables.

Autopsy identifies 16-year-old Dante Lacourte as the victim of San Francisco's first fatal cychlorphine overdose; police arrest four and seize 20,000 pills.

Prosecutors: two Jacksonville brothers sold 'fent free' counterfeit oxycodone pills that actually contained nitazenes, opioids rivaling fentanyl's potency.

Luzerne County officials warn that 12 overdose deaths in three months involved cocaine mixed with fentanyl, even as the county's overall overdose toll falls.

Singing River Health System's free naloxone vending machines at three Mississippi Gulf Coast hospitals have distributed more than 7,800 boxes as overdose deaths fall statewide.

August 31 marks 25 years of International Overdose Awareness Day with theme '25 Years On. Still Needed' as CDC reports third consecutive year of declining overdose deaths.

Middlesex-London Health Unit data shows opioid deaths fell to 62 in 2025 from 72 in 2024, marking three years of progress while officials warn gains remain fragile.

Wisconsin records steepest-ever single-year drop in fentanyl overdose deaths, falling from 1,422 in 2023 to 818 in 2024, as naloxone destigmatization and treatment access expand.

Pennsylvania's Department of Drug and Alcohol Programs introduces free self-paced online naloxone training, with over 100 residents completing the course in the first two weeks.

Ocean County's first 24/7 harm reduction vending machine opens in Toms River, providing free naloxone, sterile syringes, and overdose prevention supplies anonymously.

The iNal patch uses microneedle technology to detect dangerous fentanyl levels and automatically release naloxone, potentially saving lives when no bystander is present.

Springfield, Missouri expands harm reduction infrastructure with 14 distribution boxes at fire stations, providing 24/7 access to overdose reversal kits without questions or paperwork.

Utah officials warn that Buzzers Cat's Claw tablets contained illicit kratom compounds tied to a death and multiple overdoses; retailers ordered to remove the product.

Ohio Narcotics Intelligence Center issues urgent public safety bulletins about orphine analogs and veterinary sedatives medetomidine and xylazine appearing in the state's illicit drug supply.

Oklahoma discontinues its statewide naloxone vending machine program after 16 months, shifting burden to local organizations as fentanyl deaths persist and federal harm reduction funding faces cuts.

Scienture Holdings begins shipping REZENOPY, a 10mg naloxone nasal spray—the highest FDA-approved dose—bringing a new overdose reversal option as fentanyl deaths decline nationwide.

Wisconsin reports 1,185 drug overdose deaths in 2024, a 33% decline from 2022 peak, as naloxone distribution and medication-assisted treatment expansion show measurable results.

South Carolina reports 1,481 drug overdose deaths in 2024, a 31.3% decrease from 2023, with fentanyl remaining the primary contributor to fatalities.

Howard County, Maryland deploys free naloxone vending machines providing 24/7 anonymous access to overdose reversal medication and drug testing supplies.